Targeted protein degradation (TPD) represents a novel paradigm in drug discovery that could lead to more efficient medicines to treat diseases such as cancer. 'Molecular glue degrader'are an emerging but understudied class of small molecules that have been shown to induce degradation of proteins commonly considered 'undruggable'. Researchers have described a strategy that, for the first time, enables the rational and highly scalable discovery of novel molecular glue degraders.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/08/200803120128.htm
Monday, August 3, 2020
Baby boomers show concerning decline in cognitive functioning
In a reversal of trends, American baby boomers scored lower on a test of cognitive functioning than did members of previous generations, according to a new nationwide study.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/08/200803092125.htm
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/08/200803092125.htm
Experiencing childhood trauma makes body and brain age faster
Children who suffer trauma from abuse or violence early in life show biological signs of aging faster than children who have never experienced adversity, according to new research. The study examined three different signs of biological aging -- early puberty, cellular aging and changes in brain structure -- and found that trauma exposure was associated with all three.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/08/200803092120.htm
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/08/200803092120.htm
Saturday, August 1, 2020
Gut feelings help promote positive body image
New research has found that paying greater attention to internal bodily sensations can increase our appreciation of our own bodies.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200730205826.htm
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200730205826.htm
Peering into the secrets of phages to see how they kill bacterial superbugs
A research collaboration has made an exciting discovery that may eventually lead to targeted treatments to combat drug-resistant bacterial infections, one of the greatest threats to global health.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200730110130.htm
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200730110130.htm
Friday, July 31, 2020
How human sperm really swim: New research challenges centuries-old assumption
A breakthrough in fertility science has shattered the universally accepted view of how sperm 'swim'.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200731145140.htm
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200731145140.htm
To improve students' mental health, study finds, teach them to breathe
When college students learn specific techniques for managing stress and anxiety, their well-being improves across a range of measures and leads to better mental health, a new study finds.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200731135555.htm
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/07/200731135555.htm
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