Tuesday, June 30, 2020

COVID-19: Study shows virus can infect heart cells in lab dish

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630155745.htm

A revolutionary new treatment alternative to corneal transplantation

A new approach in ophthalmology that offers a revolutionary alternative to corneal transplantation has just been developed by researchers and clinicians in North America, Europe, and Oceania.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630072042.htm

Lifting weights makes your nervous system stronger, too

Gym-goers may get frustrated when they don't see results from weightlifting right away, but their efforts are not in vain: the first few weeks of training strengthen the nervous system, not muscles.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629132104.htm

Human-Artificial intelligence collaborations best for skin cancer diagnosis

Artificial intelligence (AI) improved skin cancer diagnostic accuracy when used in collaboration with human clinical checks.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120229.htm

Genomic variation causing common autoinflammatory disease may increase resilience to bubonic plague

Researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease called familial Mediterranean fever because of evolutionary pressure to survive the bubonic plague epidemics.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120225.htm

Next-generation sequencing to provide precision medicine for rare metabolic disorders

Advances in next-generation-sequencing technology that allow researchers to look at billions of pieces of genetic information are changing the way a disease is diagnosed. Correct identification of changes in the human genetic code responsible for rare metabolic disorders provides scientists and physicians with fact-based guidelines for the treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630131720.htm

Glowing dye may aid in eliminating cancer

When a solid cancer is surgically removed, any small piece that is left behind increases the chance of a local recurrence or spread. In a pilot study of dogs with mammary tumors, a disease very similar to human breast cancer, a team found that an injectable dye, which glows under near-infrared light, illuminated cancerous growth in the primary tumor as well as in lymph nodes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630125128.htm

Universal gut microbiome-derived signature predicts cirrhosis

Researchers report that stool microbiomes of NAFLD patients are distinct enough to potentially be used to accurately predict which persons with NAFLD are at greatest risk for having cirrhosis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630125126.htm

Researchers identify multiple molecules that shut down SARS-Cov-2 polymerase reaction

Researchers have identified a library of molecules that shut down the SARS-CoV-2 polymerase reaction, a key step that establishes the potential of these molecules as lead compounds to be further modified for the development of COVID-19 therapeutics. Five of these molecules are already FDA-approved for use in the treatment of other viral infections including HIV/AIDS, cytomegalovirus, and hepatitis B.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630125124.htm

'Morning sickness' is misleading and inaccurate, new study argues

The term 'morning sickness' is misleading and should instead be described as nausea and sickness in pregnancy, argue researchers who have demonstrated that these symptoms can occur at any time of the day -- not just the morning.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630111438.htm

Novel pathology could improve diagnosis and treatment of Huntington's and other diseases

Scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease. The article describes how SAFB1 expression occurs in both spinocerebellar ataxias and Huntington's disease and may be a common marker of these conditions, which have a similar genetic background.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630103612.htm

Whole-town study reveals more than 40% of COVID-19 infections had no symptoms

A study of COVID-19 in the quarantined Italian town of Vò, where most of the population was tested, reveals the importance of asymptomatic cases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630103557.htm

COVID-19 causes 'hyperactivity' in blood-clotting cells

Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease, according to scientists. The researchers found that inflammatory proteins produced during infection significantly alter the function of platelets, making them 'hyperactive' and more prone to form dangerous and potentially deadly blood clots.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630125129.htm

Light drinking may protect brain function

Light to moderate drinking may preserve brain function in older age, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630125135.htm

Life-hack: Rituals spell anxiety relief

Researchers are examining the important roles rituals play in reducing our anxiety levels.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630111504.htm

Discovery of key protein behind cancer relapse and progression can lead to new therapies

Reports show that cancer is the second-highest leading cause of death globally. A recent study by scientists provides new evidence supporting the presence of a key mechanism behind progression and relapse in cancer. The study discusses the role of MBNL1 protein as a biomarker for cancer prognosis, which can lead to the development of new treatment strategies for cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630103610.htm

Lab-grown 'mini-brains' suggest COVID-19 virus can infect human brain cells

Researchers have found that organoids known as 'mini-brains' can be infected by the SARS-CoV-2 virus that causes COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630111445.htm

Supreme Court Upholds Anti-Prostitution Pledges in AIDS Funding

The federal government can require foreign affiliates of U.S. companies to denounce sex work in order to secure HIV funding.


from POZ RSS - Categories https://www.cancerhealth.com/article/supreme-court-upholds-antiprostitution-pledges-aids-funding

Promising therapy for cardiac regeneration

New research gives information in order to understand safety, efficacy and mechanisms of action of a new cardiac therapy.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630103605.htm

A vaccine targeting aged cells mitigates metabolic disorders in obese mice

Researchers developed a novel vaccine that removes senescent T cells from adipose tissues. They showed that vaccinated obese mice had improved glucose tolerance and insulin resistance without showing severe adverse events. These findings could help develop a novel therapeutic tool.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630103601.htm

Implants: Can special coatings reduce complications after implant surgery?

New coatings on implants could help make them more compatible. Researchers at the Martin Luther University Halle-Wittenberg (MLU) have developed a new method of applying anti-inflammatory substances to implants in order to inhibit undesirable inflammatory reactions in the body.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200630072047.htm

New treatment for common form of muscular dystrophy shows promise in cells, animals

Researchers have designed a potential new treatment for one of the most common forms of muscular dystrophy. Medical researchers have created and tested synthetic DNA-like molecules that interfere with the production of a toxic protein that destroys the muscles of people who have facioscapulohumeral muscular dystrophy (FSHD).

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629164141.htm

Preterm delivery increases long-term risks of ischemic heart disease in women throughout their life

Women who gave birth before their 37th week of pregnancy are at an increased risk of developing ischemic heart disease (IHD) over the course of their life independent of other risk factors such as BMI or smoking, according to a new study. The study findings suggest reproductive history should be routinely included in cardiovascular risk assessments of women.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629150552.htm

Closer threats inspire a more primitive kind of fear

Your brain handles a perceived threat differently depending on how close it is to you. If it's far away, you engage more problem-solving areas of the brain. But up close, your animal instincts jump into action and there isn't as much reasoning. And that is probably what makes it harder to extinguish the fear of a close-up threat and more likely that you'll have some long-term stress from the experience.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629150542.htm

Raw milk may do more harm than good

Raw or unpasteurized cows' milk from U.S. retail stores can hold a huge amount of antimicrobial-resistant genes if left at room temperature, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629140054.htm

Monday, June 29, 2020

New eye drops may prevent a common cause of blindness

New eye drops could prevent vision loss after retinal vein occlusion, a major cause of blindness for millions of adults, a study has found.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629140023.htm

Microbiome confers resistance to cholera

Many parts of the world are in the midst of a deadly pandemic of cholera, an extreme form of watery diarrhea. Scientists have discovered specific gut bacteria make some people resistant to it -- a finding that could save lives.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629132059.htm

Excessive sugar intake linked with unhealthy fat deposits

Sugar consumption is linked with larger fat deposits around the heart and in the abdomen, which are risky for health.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120243.htm

Declining eyesight improved by looking at deep red light

Staring at a deep red light for three minutes a day can significantly improve declining eyesight, finds a new study, the first of its kind in humans.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120241.htm

Institutional Racism Affects COVID-19’s Impact on African Americans

Anthony Fauci, MD, highlighted how socioeconomic status contributes to racial disparities during the coronavirus pandemic.


from POZ RSS - Categories https://www.cancerhealth.com/article/institutional-racism-affects-covid19s-impact-african-americans

Ladder falls have long-lasting consequences for older men

In the world's first study of long-term impacts from ladder falls, researchers have found half of fallers experience a deterioration in their psychological well-being for at least six months after the incident.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120231.htm

Study finds exercise increases benefits of breast milk for babies

A new study finds even moderate exercise during pregnancy increases a compound in breast milk that reduces a baby's lifelong risks of serious health issues such as diabetes, obesity and heart disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120220.htm

Bioengineered uteri support pregnancy

Scientists were able to show that bioengineered uteri in an animal model developed the native tissue-like structures needed to support normal reproductive function.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120217.htm

Air pollution's connection to infant mortality

The study of sub-Saharan Africa finds that a relatively small increase in airborne particles significantly increase infant mortality rates. A cost-effective solution may lie in an exotic-sounding proposal.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120215.htm

Producing a gaseous messenger molecule inside the body, on demand

Method could shed light on nitric oxide's role in the neural, circulatory, and immune systems.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120213.htm

Laser-welded sugar: Sweet way to 3D-print blood vessels

Bioengineers have shown they can keep densely packed cells alive in lab-grown tissues by creating complex networks of branching blood vessels from templates of 3D-printed sugar.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120203.htm

Engineers use 'DNA origami' to identify vaccine design rules

Using DNA origami as a virus-like scaffold, researchers designed an HIV-like particle that provokes a strong response from human immune cells grown in the lab. They are now testing this approach as a potential vaccine candidate in live animals, and adapting it to SARS-CoV-2, as well as other pathogens.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120159.htm

The gut shields the liver from fructose-induced damage

After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center study. However, the consumption of too much fructose -- particularly in a short period of time -- can overwhelm the gut, causing fructose to ''spill over'' into the liver, where it wreaks havoc and causes fatty liver, researchers discovered.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120250.htm

Even minor heart defects are associated with long-term problems in adulthood

Long-term morbidity as well as a lower level of education and employment rate are common among adults who underwent congenital heart surgery during childhood, regardless of the severity of the defect.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120149.htm

Clostridium difficile: Fecal microbial transplantation more effective and less costly than antibiotics

An innovative treatment for patients with Clostridium difficile infection (CDI) which uses transplanted gut bacteria to treat the infection, is a more effective and more cost-efficient treatment than using antibiotics, a new study has found.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120129.htm

Why the Abortion Ruling Is Good News for HIV Health Efforts

The Supreme Court struck down a Louisiana law that would have shuttered most abortion clinics.


from POZ RSS - Categories https://www.cancerhealth.com/article/abortion-ruling-good-news-hiv-health-efforts

Engineered immune cells recognize, attack human and mouse solid-tumor cancer cells

CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia. It modifies a patient's own T-cells by adding a piece of an antibody that recognizes unique features on the surface of cancer cells. In a new study, researchers report that they have dramatically broadened the potential targets of this approach - their engineered T-cells attack a variety of solid-tumor cancer cells from humans and mice.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629120120.htm

Blood pressure connected to eye health in young children

Children with impaired microvascular health developed higher systolic blood pressure over the course of a four-year study. Narrowing of retinal arteries in children who began the study with normal blood pressure predicted development of high blood pressure during early childhood.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629090016.htm

Ecosystem degradation could raise risk of pandemics

Environmental destruction may make pandemics more likely and less manageable, new research suggests.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200629090009.htm

Saturday, June 27, 2020

Promising treatment to slow kidney disease doesn't prove out in clinical trial

Progression of kidney disease in type 1 diabetes is correlated with increased amounts of uric acid. A drug that reduces uric acid levels was tested in a multi-institution randomized clinical trial. Though the study did not show the desired clinical benefit, it did provide a very clear answer to an important scientific question.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200627112431.htm

Repeated head impacts associated with later-life depression symptoms, worse cognitive function

In the largest study of its kind, an association has been found in living patients exposed to repetitive head impacts and difficulties with cognitive functioning and depression years or decades later.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626161159.htm

Researchers destroy cancer cells with ultrasound treatment

An international research team has developed a noninvasive technology platform for gene delivery into breast cancer cells. The technique combines ultrasound with tumor-targeted microbubbles.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626141415.htm

Designer peptides show potential for blocking viruses, encourage future study

Chemically engineered peptides could prove valuable in the battle against some of the most persistent human health challenges. New findings demonstrate how researchers can engineer peptides capable of selectively and specifically binding to polysialic acid (PSA) -- a carbohydrate that is present in many human cells and plays a key role in various physiological and pathological processes, including neurological development and disease progression.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626125023.htm

New protein complex gets chromosomes sorted

Researchers have identified a novel protein complex that regulates Aurora B localization to ensure that chromosomes are correctly separated during cell division. The complex, NWC, is made up of three proteins: NOL11, WDR43, and Cirhin. In the absence of NWC, Aurora B did not accumulate at centromeres, and chromosome movement and alignment were impaired. Together, these results show that NWC is required for faithful chromosome segregation.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626114823.htm

From the lab, the first cartilage-mimicking gel that's strong enough for knees

The thin, slippery layer of cartilage between the bones in the knee is magical stuff: strong enough to withstand a person's weight, but soft and supple enough to cushion the joint against impact, over decades of repeat use. That combination of soft-yet-strong has been hard to reproduce in the lab. But now, researchers say they've created an experimental gel that's the first to match the strength and durability of the real thing.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626114755.htm

Marine training may take more mental than physical grit

A new study identifies psychological measures that may predict who is more likely to complete - or quit - a demanding marine training course.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626092737.htm

Comparing 13 different CRISPR-Cas9 DNA scissors

Scientists have achieved the most extensive high-throughput analysis of CRISPR-Cas9 activities. The team developed deep-learning-based computational models that predict the activities of SpCas9 variants for different DNA sequences. This study represents a useful guide for selecting the most appropriate SpCas9 variant.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626092729.htm

Long-term use of muscle relaxants has skyrocketed since 2005

Researchers found the drugs were prescribed disproportionately to older adults, often concurrently with opioids, despite warnings against this dangerous combination.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626092721.htm

Critical new allergy pathway

Researchers have identified the sequence of molecular events by which tiny, tick-like creatures called house dust mites trigger asthma and allergic rhinitis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625162254.htm

Microbiome of anticancer compound-producing marine invertebrate

Could the cure for melanoma - the most dangerous type of skin cancer -- be a compound derived from a marine invertebrate that lives at the bottom of the ocean? A group of scientists think so, and are looking to the microbiome of an Antarctic ascidian called Synoicum adareanum to better understand the possibilities for development of a melanoma-specific drug.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625162248.htm

Scientists devise new 'bar code' method to identify critical cell types in the brain

A discovery could pave the way for future studies aimed at developing solutions to ALS and other vexing neuromuscular diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625162245.htm

Friday, June 26, 2020

Hepatitis A Outbreaks Are Again Cropping Up Nationwide

Several states are reporting a rise in cases of the infectious liver disease.


from POZ RSS - Categories https://www.cancerhealth.com/article/hepatitis-outbreaks-cropping-nationwide

More evidence of causal link between air pollution and early death

Strengthening U.S. air quality standards for fine particulate pollution to be in compliance with current World Health Association (WHO) guidelines could save more than 140,000 lives over the course of a decade, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626141413.htm

Common food additive causes adverse health effects in mice

A common food additive, recently banned in France but allowed in the US and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625162252.htm

Tracking the spread of mosquito insecticide resistance across Africa

In a step toward better control of the mosquitoes that transmit malaria, researchers have mapped the patterns of insecticide resistance in Anopheles gambiae mosquitoes across Africa. The new study found that resistance to five mainstream insecticides increased dramatically between 2005 and 2017.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625140737.htm

National HIV Testing Day 2020 [VIDEO]

NHTD is Saturday, June 27, and the theme is “Knowing.” Watch Admiral Brett P. Giroir, MD, explain what that means.


from POZ RSS - Categories https://www.cancerhealth.com/article/national-hiv-testing-day-2020-video

Unique Ways to Learn Your HIV Status During COVID-19

Georgia gets revved up about drive-through HIV testing. Some folks in Florida can pick up free at-home tests.


from POZ RSS - Categories https://www.cancerhealth.com/article/unique-ways-learn-hiv-status-covid19

Global economic stability could be difficult to recover in the wake of COVID-19 pandemic, finds study

New analysis suggests that the economies of countries such as America, the United Kingdom and Germany should prepare for a long slow recovery with prolonged periods of instability.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626114759.htm

Children more resilient against coronavirus, study reveals

Most children with COVID-19 fared better than adults during the first four months of the pandemic, according to a systematic review of 131 studies worldwide.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626114746.htm

Many families must 'dance' their way to COVID-19 survival, study finds

Researchers have been studying how families plan ahead and make decisions about family care and family consumption for a long time -- but what happens when planning ahead is not possible? When consumers can't plan ahead, they 'dance'.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626114745.htm

Measuring air pollution could help London transport planners fight COVID-19

Measuring air quality across London could help fight COVID-19 by providing a rapid means of deciding whether to reduce public transport movement -- given strong links between exposure to air pollution and COVID-19 transmission, a new study reveals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626114741.htm

EMS calls have dropped 26 percent nationwide in U.S. since the start of the pandemic

Since early March and the start of the COVID-19 pandemic in the United States, 911 calls for emergency medical services have dropped by 26.1 percent compared to the past two years.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626092735.htm

Estimating COVID-19 spread by looking at past trends of influenza-like illnesses

In order to better understand the spread of the novel coronavirus, new research examines trends in visits to outpatient clinics for influenza-like illnesses in March 2020 as compared to previous years.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200626092732.htm

COVID-19 costs primary care billions

On average, a full-time primary care physician in the U.S. will lose more than $65,000 in revenue in 2020. Overall, the U.S. primary care sector will lose nearly $15 billion. Losses stem from drastic reductions in office visits and fees for services during COVID-19 shutdowns from March to May. Losses threaten practice viability, reducing further an already insufficient number of primary care providers in the United States.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625162250.htm

X-rays size up protein structure at the 'heart' of COVID-19 virus

Researchers have performed the first room temperature X-ray measurements on the SARS-CoV-2 main protease -- the enzyme that enables the virus to reproduce. It marks an important first step in the ultimate goal of building a comprehensive 3D model of the enzymatic protein that will be used to advance supercomputing simulations aimed at finding drug inhibitors to block the virus's replication mechanism and help end the COVID-19 pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625162247.htm

Thursday, June 25, 2020

Unexpected mental illnesses found in a spectrum of a rare genetic disorder

Researchers found an unexpected spectrum of mental illnesses in patients with a rare gene mutation. These patients had a ''double hit'' condition that combined features and symptoms of fragile X syndrome and premutation disorder, in addition to a range of psychiatric symptoms. The findings revealed the need for clinicians to consider the complexities of the co-existing conditions of patients with both psychological and fragile X associated disorders.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625102538.htm

Novel function of platelets in tumor blood vessels found

Scientists have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which makes blood-vessel walls selectively impermeable, thereby reducing the spread of tumor cells to other parts of the body.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625080937.htm

Females use anti-inflammatory T cells to keep their blood pressure down

In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624211019.htm

$35.8M Renewed for Federal HIV/AIDS Housing Programs

HOPWA awarded the funding to these 31 grantees.


from POZ RSS - Categories https://www.cancerhealth.com/article/358m-renewed-federal-hivaids-housing-programs

Receptor makes mice strong and slim

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers have discovered a receptor in mice that regulates both effects. Experiments with human cell cultures suggest that the corresponding signaling pathways might also exist in humans.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625115916.htm

One-time treatment generates new neurons, eliminates Parkinson's disease in mice

Researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice's Parkinson's disease symptoms disappear.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625102540.htm

New study looks at post-COVID-19 emerging disease in children

In recent weeks, a multisystem hyperinflammatory condition has emerged in children in association with prior exposure or infection to SARS-CoV-2. A new case series examines the spectrum of imaging findings in children with the post-COVID-19 inflammatory condition known in the US as Multisystem Inflammatory Syndrome in Children (MIS-C).

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625140719.htm

Dangerous tick-borne bacterium extremely rare in New Jersey

There's some good news in New Jersey about a potentially deadly tick-borne bacterium. Researchers examined more than 3,000 ticks in the Garden State and found only one carrying Rickettsia rickettsii, the bacterium that causes Rocky Mountain spotted fever. But cases of tick-borne spotted fevers have increased east of the Mississippi River, and more research is needed to understand why.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625124939.htm

Driving bacteria to produce potential antibiotic, antiparasitic compounds

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of the drugs actinomycin and streptomycin and are known to harbor other untapped chemical riches.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625122735.htm

First successful delivery of mitochondria to liver cells in animals

This experiment marks the first time researchers have ever successfully introduced mitochondria into specific cells in living animals. The study lays the groundwork to address a serious gap in treatment for liver diseases and may even eventually be used to treat other maladies throughout the body affected by mitochondrial malfunction or damage.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625122732.htm

Three potential new targets for treating epilepsy

A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be controlled with current treatments.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200625115917.htm

Countries with early adoption of face masks showed modest COVID-19 infection rates

Regions with an early interest in face masks had milder COVID-19 epidemics, experts say.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624082657.htm

Entry point for curbing the evolution of antibiotic resistance discovered

Medical researchers have developed a new approach to improving the effectiveness of antibiotics in bacterial infections. The study outlines ways to controlling antibiotic resistance through targeted gene interactions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624151539.htm

Turning alcohol into key ingredients for new medicines

Chemists have found a way to turn alcohol into amino acids, the building blocks of life.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624103255.htm

Genetic malfunction of brain astrocytes triggers migraine

Neuroscientists shed a new light on the mechanisms responsible for familial migraine: They show that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624103245.htm

Treating leukaemia more effectively

Acute lymphoblastic leukaemia (ALL) is the most common kind of cancer in children. T-ALL, a subtype that resembles T-lymphocytes, can be treated successfully with the drug nelarabine. The drug has not been successful, however, with B-ALL, a subtype resembling B-lymphocytes. This has puzzled oncologists sinced the 1980's. Now researchers have discovered the reason: B-ALL cells contain the enzyme SAMHD1, which deactivates the drug.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624103243.htm

Economic alien plants more likely to go wild

Ecologist have compiled a global overview of the naturalization success of economic plants, showing that economic use in general, as well as the number and nature of economic uses, are crucial to their establishment in the wild.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624103241.htm

Molecular simulations show how drugs block key receptors

Many pharmaceuticals work by targeting what are known as ''G-protein-coupled receptors''. In a new study, scientists describe how they have been able to predict how special molecules that can be used in new immunotherapy against cancer bind to these receptors. The researchers' calculation methods are a vital contribution to future structure-based drug design.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624103238.htm

Biomedical researchers get closer to why eczema happens

A new study may help to peel back the layers of unhealthy skin -- at least metaphorically speaking -- and get closer to a cure.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624100053.htm

Medicinal cannabis may reduce behavioral problems in kids with intellectual disabilities

Cannabidiol, a type of medicinal cannabis, may reduce severe behavioral problems in children and adolescents with an intellectual disability a new study has found.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624100039.htm

Bringing burnt bones back to 'life' using 3D technology

Forensic scientists have discovered a new way of presenting fragile evidence, by reconstructing a 'jigsaw' of human bone fragments using 3D printing. In the first known study of its kind, researchers took fragmented burnt human bones and tested the ability to make 3D models suitable to be shown to a jury in court.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624095950.htm

Transgenic rice lowers blood pressure of hypertensive rats

In the future, taking your blood pressure medication could be as simple as eating a spoonful of rice. This 'treatment' could also have fewer side effects than current blood pressure medicines. As a first step, researchers have made transgenic rice that contains several anti-hypertensive peptides. When given to hypertensive rats, the rice lowered their blood pressure.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624082715.htm

Faulty brain processing of new information underlies psychotic delusions

Problems in how the brain recognizes and processes novel information lie at the root of psychosis, researchers have found. Their discovery that defective brain signals in patients with psychosis could be altered with medication paves the way for new treatments for the disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623225439.htm

Wednesday, June 24, 2020

Inflammatory bowel disease linked to doubling in dementia risk

Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is linked to a more than doubling in the risk of developing dementia, finds new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623185240.htm

Simple device monitors health using sweat

A device that monitors health conditions in the body using a person's sweat has been developed.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623185232.htm

Air pollution major risk for cardiovascular disease regardless of country income

From low-income countries to high-income countries, long-term exposure to fine particulate outdoor air pollution is a major contributor to cardiovascular disease and death, a new study found. But even small reductions in air pollution levels can result in a reduction of disease risk.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623145400.htm

Study confirms 'classic' symptoms of COVID-19

A persistent cough and fever have been confirmed as the most prevalent symptoms associated with COVID-19, according to a major review of the scientific literature.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624100047.htm

Researchers develop low-cost, easy-to-use emergency ventilator for COVID-19 patients

A team of engineers and physicians has developed a low-cost, easy-to-use emergency ventilator for COVID-19 patients that is built around a ventilator bag usually found in ambulances.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624100041.htm

Scientists uncover new genetic mutations linked to autism spectrum disorder

Scientists have identified mutations in a gene called CNOT1 that affect brain development and impair memory and learning. The research also revealed that CNOT1 interacts with several known autism spectrum disorder (ASD) genes, opening new research avenues for the condition.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624082710.htm

Defining paths to possible mother to child coronavirus transmission

Researchers took a critical step in defining the possible paths for SARS-CoV-2 causing COVID-19 to get transmitted from the mother to her newborn baby.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623185228.htm

Three-quarters of US workers can't work exclusively from home, face greater risks during pandemic

About three-quarters of US workers, or 108 million people, are in jobs that cannot be done from home during a pandemic, putting these workers at increased risk of exposure to disease. This majority of workers are also at higher risk for other job disruptions such as layoffs, furloughs or hours reductions, a new study shows.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623145320.htm

COVID-19: Herd immunity threshold could be lower, study finds

Herd immunity to COVID-19 could be achieved with less people being infected than previously estimated, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623111329.htm

New research confirms higher rates of new coronavirus in Latinx populations

A study of testing results across Johns Hopkins Medicine testing sites highlights coronavirus racial disparities in the Baltimore-Washington area.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623100117.htm

Urine test reveals quality of your diet -- and whether it's the best fit for your body

Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622133026.htm

SARS-CoV-2: New insights on antibody testing and RNA testing

Two new papers address testing modalities for tracking SARS-CoV-2. Reverse transcriptase PCR (rt-PCR) tests for current infection. Antibody tests reveal that an infection has taken place, even long after the fact.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622132952.htm

A second COVID-19 wave could be avoided if social distancing and the use of face masks are maintained, study finds

A model developed by ISGlobal shows that deconfinement must be gradual and that individual behaviour is a key factor.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622132943.htm

Scientists support the use of ultraviolet light to reduce SARS-CoV-2 transmission indoors

An international team of researchers advocates the use of UV-C light in indoor spaces as a way to reduce the transmission of SARS-CoV-2 viruses. This solution meets the requirements of fast, scalable, and affordable implementation to fulfill the needs of disinfecting working spaces, such as offices, schools, healthcare facilities, and public transportation, to name a few.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622132941.htm

Early pandemic paradox: Fewer UK deaths from December 2019 to March 2020 compared to the previous 5 years

An analysis of national weekly mortality rates in the United Kingdom between December 2019 and March 2020, compared to the same period for the previous five years, has shown that there have been fewer deaths registered this year during the lead up to the Covid-19 pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622132935.htm

Wildfire smoke has immediate harmful health effects

Exposure to wildfire smoke affects the body's respiratory and cardiovascular systems almost immediately, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200624100045.htm

New adjuvant successful in extending immunity against HIV

Emory researchers are the first to show a new adjuvant, 3M-052, helps induce long-lasting immunity against HIV. This finding has implications for developing successful vaccines against HIV, influenza and COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200620141952.htm

Current serotype of dengue virus in Singapore disguises itself to evade vaccines and therapeutics

Singapore saw 1,158 dengue cases in the week ending 13 June 2020, the highest number of weekly dengue cases ever recorded since 2014. The dengue virus serotype 3 (DENV3), which is currently circulating in Singapore, can undergo dramatic structural changes that enable it to resist vaccines and therapeutics, reveal findings from a new study. The findings could guide the development of effective vaccines and therapeutics against dengue infection.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623104236.htm

Tongue microbes provide window to heart health

Microorganisms on the tongue could help diagnose heart failure, according to new research. 'The tongues of patients with chronic heart failure look totally different to those of healthy people,' said one of the researchers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623100126.htm

Reducing the damage of a heart attack

Cardiology researchers have discovered how a key protein can help the heart regulate oxygen and blood flow and repair damage.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623100119.htm

New class of precision medicine strips cancer of its DNA defenses

A new precision medicine targeting cancer's ability to repair its DNA has shown promising results in the first clinical trial of the drug class. The new study, designed to test the drug's safety, found that half of patients given the new drug either alone or with platinum chemotherapy saw their cancer stop growing, and two patients saw their tumours shrink or disappear completely.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622160339.htm

Super-strong surgical tape detaches on demand

Engineers have designed a super-strong, detachable adhesive that may someday replace surgical sutures.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622152517.htm

Pioneering research reveals certain human genes relate to gut bacteria

The role genetics and gut bacteria play in human health has long been a fruitful source of scientific inquiry, but new research marks a significant step forward in unraveling this complex relationship. Its findings could transform our understanding and treatment of all manner of common diseases, including obesity, irritable bowel syndrome, and Alzheimer's disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622133018.htm

COVID-19 Could Cause a Shortage of HIV Meds This Summer

The global supply of tenofovir and six other important generic drugs must be ensured, warns a UNAIDS analysis.


from POZ RSS - Categories https://www.cancerhealth.com/article/covid19-cause-shortage-hiv-meds-summer

Tuesday, June 23, 2020

Gear treated with 'forever chemicals' poses risk to firefighters

Researchers tested more than 30 samples of used and unused PPE from six specialty textile manufacturers in the United States and found them to be treated extensively with PFAS or constructed with fluoropolymers, a type of PFAS used to make textiles oil and water resistant.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623145336.htm

Scientists use protein, RNA to make hollow, spherical sacks called vesicles

Using protein and RNA, scientists have created hollow, spherical sacks known as vesicles. These bubble-like entities -- which form spontaneously when specific protein and RNA molecules are mixed in an aqueous buffer solution -- hold potential as biological storage compartments. They could serve as an alternative to traditional vesicles that are made from water-insoluble organic compounds called lipids, researchers say.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623145312.htm

Does 'mommy brain' last? Study shows motherhood does not diminish attention

'Mommy brain' is a long-held perception that mothers are more forgetful and less attentive. A new study shows that mothers are equally as attentive, or more attentive than, non-mothers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623145352.htm

Universal flu vaccine may be more challenging than expected

Some common strains of influenza have the potential to mutate to evade broad-acting antibodies that could be elicited by a universal flu vaccine, according to a new study. The findings highlight the challenges involved in designing such a vaccine, and should be useful in guiding its development.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623145350.htm

Prenatal stress associated with infant gut microbes

Mother's chronic prenatal psychological distress and elevated hair cortisol concentrations are associated with gut microbiota composition of the infant, according to a new publication. The results help to better understand how prenatal stress can be connected to infant growth and development.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623145346.htm

Environmental conditions found to affect stability of virus that causes COVID-19

A new study found that environmental conditions affect the stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human nasal mucus and sputum.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619143435.htm

Babies with COVID-19 tend to have mild illness, mostly with fever

A new report shows that infants under 90 days of age who tested positive for COVID-19 tend to be well, with little or no respiratory involvement. Fever was often found to be the primary or only symptom.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619143433.htm

MMR vaccine could protect against the worst symptoms of COVID-19

Administering the MMR (measles, mumps, rubella) vaccine could serve as a preventive measure to dampen septic inflammation associated with COVID-19 infection, say experts.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619090602.htm

Fighting the COVID-19 pandemic through testing

Research labs are racing to develop innovative testing methods and overcome the bottlenecks to more widespread testing, which is crucial to controlling the spread of the disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619090455.htm

A furry social robot can reduce pain and increase happiness

Researchers have discovered that a single, 60-minute interaction with PARO actually improved mood as well as reduced mild or severe pain. When participants touched PARO, they experienced greater pain reduction than when it was simply present in their room.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200623100115.htm

Social and behavioral factors most closely associated with dying

Smoking, divorce and alcohol abuse have the closest connection to death out of 57 social and behavioural factors analyzed in this study. The researchers analyzed data collected from 13,611 adults in the U.S. between 1992 and 2008, and identified which factors applied to those who died between 2008 and 2014. They intentionally excluded biological and medical factors.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622152521.htm

$14M Federal Grant to Research CAR-T Gene Therapy to Cure HIV

This strategy entails genetically modifying a person’s stem cells to target and destroy cells infected with HIV.


from POZ RSS - Categories https://www.cancerhealth.com/article/14m-federal-grant-research-cart-gene-therapy-cure-hiv

Monday, June 22, 2020

Decline in green energy spending might offset COVID-era emissions benefits

Researchers have documented short-term environmental benefits during the COVID-19-related lockdown, but that silver lining could be far outweighed by a long-term decline on clean energy investments, a new study finds.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622182208.htm

Immune cells infiltrating tumors may play bigger cancer role than previously thought

Researchers uncovered in mice how a molecule involved in cells' response to stress determines whether macrophages promote inflammation in the tumor microenvironment. Inflammation is known to promote tumor growth, making this molecule an attractive target for drug development.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622160257.htm

Critically ill COVID-19 patients are 10 times more likely to develop cardiac arrhythmias

Patients with COVID-19 who were admitted to an intensive care unit were 10 times more likely than other hospitalized COVID-19 patients to suffer cardiac arrest or heart rhythm disorders, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622133006.htm

Hamsters develop protective immunity to COVID-19 and are protected by convalescent sera

In an animal model for COVID-19 that shares important features of human disease, scientists show that prior infection with the SARS-CoV-2 virus provides protection against reinfection, and treatment with convalescent serum limits virus replication in their lungs.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622172026.htm

Initial COVID-19 infection rate may be 80 times greater than originally reported

A new study estimates that the number of early COVID-19 cases in the U.S. may have been more than 80 times greater and doubled nearly twice as fast as originally believed.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622141143.htm

COVID-19 lockdown reveals human impact on wildlife

An international team of scientists is investigating how animals are responding to reduced levels of human activity during the Covid-19 pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622133020.htm

Household Crowding and Poverty Raise COVID-19 Risk

Among pregnant women, household density was the strongest predictor of this potentially severe respiratory illness.


from POZ RSS - Categories https://www.cancerhealth.com/article/household-crowding-poverty-raise-covid19-risk

Nuclear softening allows cells to move into dense tissue, encouraging injury repair

Using an enzyme inhibitor in meniscus cells, a new study was able to soften their nucleus and promote access to previously impassible areas.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622133055.htm

Better measure of 'good cholesterol' can gauge heart attack and stroke risk in some populations

For decades, high-density lipoprotein (HDL) cholesterol has been dubbed 'good cholesterol' because of its role in moving fats and other cholesterol molecules out of artery walls. People with higher HDL cholesterol levels tend to have lower rates of cardiovascular disease, studies have shown.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622132957.htm

Smokers good at math are more likely to want to quit

For smokers who are better at math, the decision to quit just adds up, a new study suggests. Researchers found that smokers who scored higher on a test of math ability were more likely than others to say they intended to quit smoking.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622095043.htm

Online program improves insomnia in adolescent and young adult cancer survivors

Researchers show that an online program developed specifically for AYA cancer survivors can significantly alleviate insomnia and improve overall quality of life.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622095037.htm

This enigmatic protein sculpts DNA to repair harmful damage

Sometimes, when something is broken, the first step to fixing it is to break it even more. Scientists have discovered this is the case for a DNA-repairing enzyme that marks then further breaks damaged DNA. Their surprising findings have provided much-needed insight into how DNA repair works in healthy cells, as well as how different mutations can translate into different diseases and cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622095035.htm

Vitamin D may help prevent a common side effect of anti-cancer immunotherapy

published in CANCER indicates that taking vitamin D supplements may help prevent a potentially serious side effect of a revolutionary form of anti-cancer therapy.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622095018.htm

Breakthrough discovery to transform prostate cancer treatment

A novel formulation of the prostate cancer drug abiraterone acetate - currently marketed as Zytiga - will dramatically improve the quality of life for people suffering from prostate cancer, as pre-clinical trials show the new formulation improves the drug's effectiveness by 40 per cent.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200620141948.htm

Crowded homes, poor neighborhoods linked to COVID-19

A study of nearly 400 pregnant women is among the first to show that socioeconomic status and household crowding increase the risk of getting COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618124756.htm

COVID-19 affects adolescent and young adults sexual and reproductive health

Social distancing and limited access to contraceptive and abortion care during the COVID-19 pandemic is affecting the sexual and reproductive health of adolescents and young adults according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618124754.htm

Higher rates of severe COVID-19 in BAME populations remain unexplained

Higher rates of severe COVID-19 infections in Black, Asian and Minority Ethnic (BAME) populations are not explained by socioeconomic or behavioral factors, cardiovascular disease risk, or by vitamin D status, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619115713.htm

Boston partnership leverages local manufacturing to quickly produce reusable face shields

Researchers at a major Boston academic medical center designed, fabricated, tested, and implemented a reusable face shield for front-line medical staff within a couple of weeks.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618124746.htm

First known case of a potentially deadly heart rhythm disturbance induced by chloroquine therapy for COVID-19 reported

Clinicians should carefully monitor patients treated with chloroquine therapy, particularly elderly women and others at higher risk for heart rhythm abnormalities, investigators caution in new article.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618120201.htm

Clear signs of brain injury with severe COVID-19

Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neurochemical signs of brain injury, a new study shows. In even moderate COVID-19 cases, finding and measuring a blood-based biomarker for brain damage proved to be possible.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618111009.htm

Urban density not linked to higher coronavirus infection rates, study finds

A new study suggests that denser places, assumed by many to be more conducive to the spread of the coronavirus that causes COVID-19, are not linked to higher infection rates.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618110953.htm

Diabetic ketoacidosis threatens hospitalized patients with COVID-19

Diabetic ketoacidosis is a common and potentially fatal complication in hospitalized patients with COVID-19, according to a new clinical perspective.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618092447.htm

The Health Not Prisons Collective Is Launched to Reform HIV Crime Laws

Plus: The Elizabeth Taylor AIDS Foundation and Gilead Sciences join the collective for a virtual town hall June 25.


from POZ RSS - Categories https://www.cancerhealth.com/article/health-prisons-collective-launched-reform-hiv-crime-laws

Medicinal leech genome sequenced

A new study offers insights into the powerful anticoagulants contained in the saliva of leeches most often used in medical practice.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618073542.htm

COVID-19 toll in nursing homes linked to staffing levels and quality

A new study shows that residents of long-term care facilities with lower nurse staffing levels, poorer quality scores, and higher concentrations of disadvantaged residents suffer from higher rates of confirmed COVID-19 cases and deaths.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618073538.htm

Sugary drink tax models show health gains, cost reductions, but vary by tax design

A simulation model details how different taxing strategies for sodas and other sugary drinks could impact health gains linked to heart attacks, strokes and diabetes while also lowering health care costs in the US. Three types of taxation on sugary drinks lower healthcare costs, cardiovascular disease, and diabetes, but some -- such as taxing sugar content -- perform even better than taxing based on the volume of the beverage.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200622095014.htm

Sunday, June 21, 2020

Shining light on a malignant lung cancer

Treating a rare type of malignant lung cancer could improve, thanks to near-infrared irradiation and a cancer-targeting compound.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200620141950.htm

Saturday, June 20, 2020

Adolescents from disadvantaged neighborhoods show gene regulation differences

An 18-year study of 2,000 children born in England and Wales found that young adults raised in communities marked by more economic deprivation, physical dilapidation, social disconnection, and danger display differences in the epigenome -- the proteins and chemical compounds that regulate the activity of their genes. The findings suggest that gene regulation may be one biological pathway through which neighborhood disadvantage 'gets under the skin' to engender long-term health disparities.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619115704.htm

The rate we acquire genetic mutations could help predict lifespan, fertility

Differences in the rate that genetic mutations accumulate in healthy young adults could help predict remaining lifespan in both sexes and the remaining years of fertility in women, according to scientists. Their study, believed to be the first of its kind, found that young adults who acquired fewer mutations over time lived about five years longer than those who acquired them more rapidly.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619090528.htm

Silicosis: Ominous resurgence of an occupational lung condition reported

A new study documents an increased incidence of silicosis, which progressed rapidly to massive pulmonary fibrosis in a significant proportion of patients who had previously worked artificial stone (AS), also called artificial quartz agglomerate or conglomerate, a popular new countertop material, despite cessation of exposure after diagnosis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618073543.htm

Friday, June 19, 2020

Renewed hope for treatment of pain and depression

Researchers have developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby modulating the levels of opioid peptides produced in the central nervous system (CNS) and potentiating their natural painkilling and antidepressant properties.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619090522.htm

New light shone on inflammatory cell death regulator

Australian researchers have made significant advances in understanding the inflammatory cell death regulatory protein MLKL and its role in disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619090503.htm

How cancer drugs find their targets could lead to a new toolset for drug development

Cellular processes such as transcription often take place in tiny cellular droplets called condensates. A new study shows the mechanism by which small molecules, including cancer drugs, are concentrated in these droplets -- a finding that could have implications for the development of new cancer therapeutics. If researchers could tailor a chemical to seek out and concentrate in one kind of droplet in particular, it might have a positive effect on the delivery efficiency of the drug.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618150308.htm

Memory impairment in mice reduced by soy derivate that can enter the brain intact

Researchers have found that a soy-derived protein fragment that reaches the brain after being ingested reduces memory degradation in mice with an induced cognitive impairment, providing a new lead for the development of functional foods that help prevent mental decline.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619104312.htm

Physical activity prevents almost 4 million early deaths worldwide each year

At least 3.9 million early deaths are being averted worldwide every year by people being physically active, according to a new study using data from 168 countries. By showing how many deaths are averted, it might also be possible to frame the debate in a positive way and this could have benefits to advocacy, policy and population messaging.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617194510.htm

Fantastic muscle proteins and where to find them

Setting out to identify all proteins that make up the sarcomere, the basic contractile unit of muscle cells, resulted in an unexpected revelation, providing experimental evidence that helps explain a fundamental mystery about how muscles work.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200619120839.htm

Gut bacteria may modify behavior in worms, influencing eating habits

Gut bacteria are tiny but may play an outsized role not only in the host animal's digestive health, but in their overall well-being. According to a new study, specific gut bacteria in the worm may modify the animal's behavior, directing its dining decisions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617145954.htm

Here’s Some Upbeat HIV News From Across the Pond

Courtesy of the Scottish police, Amsterdam and four cities in Ireland


from POZ RSS - Categories https://www.cancerhealth.com/article/upbeat-hiv-news-across-pond

Thursday, June 18, 2020

Sedentary behavior independently predicts cancer mortality

In the first study to look at objective measures of sedentary behavior and cancer mortality, researchers found that greater inactivity was independently associated with a higher risk of dying from cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618150311.htm

US cities with pro sports see more flu deaths

Sports leagues may want to consider calling a timeout on reopening their doors to fans, based on new research that links an uptick in seasonal flu deaths to US cities with pro sports teams.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618150310.htm

Scientists decode how the brain senses smell

Scientists have further decoded how mammalian brains perceive odors and distinguish one smell from thousands of others.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618150304.htm

Genetic variation may affect bacterial composition and healing of wounds

Genetic variability across patients might play an important role in shaping the microbiome composition of wounds, thereby influencing the healing process, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618150302.htm

Hookworm trial offers new hope to MS patients

Parasitic worms could offer a new treatment hope for patients suffering from the autoimmune disease multiple sclerosis, according to experts.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618150223.htm

Viruses can steal our genetic code to create new human-virus genes

A new study unveils a novel mechanism that allows viruses to produce unexpected proteins.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618120213.htm

Nanoparticle for overcoming leukemia treatment resistance

One of the largest problems with cancer treatment is the development of resistance to anticancer therapies. A research team found that repurposing a commonly used chemotherapy drug using a nanoparticle was more effective than both a solution of the pure drug and other available treatments.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618120149.htm

Not smoking and being socially active keys to longevity

Researchers have discovered some of the secrets to longevity with new research revealing not smoking and being social engaged throughout older age are common traits of New Zealand centenarians.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618094625.htm

A deep-learning E-skin decodes complex human motion

A deep-learning powered single-strained electronic skin sensor can capture human motion from a distance. The single strain sensor placed on the wrist decodes complex five-finger motions in real time with a virtual 3D hand that mirrors the original motions. The deep neural network boosted by rapid situation learning (RSL) ensures stable operation regardless of its position on the surface of the skin.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618094617.htm

Earth's species have more in common than previously believed

In the largest mapping of proteins ever to be conducted across different species, an international team of researchers have analysed and compared the proteins of 100 animal, plant and bacterial species. The different life forms appear to have remarkable similarities when looking at their proteins. The new study has also doubled the number of experimentally confirmed proteins.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617150006.htm

Non-invasive fetal oxygen monitor could make for safer deliveries

A device to directly measure blood oxygen saturation in a fetus during labor has been developed by researchers at UC Davis. By providing better information about the health of a fetus right before birth, the device could both reduce the rate of Cesarean sections and improve outcomes in difficult deliveries.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617145943.htm

New structural 'map' solves mysteries of gigantic gene regulator

Structural biology has been used to 'map' part of a protein called SMCHD1, explaining how some changes in SMCHD1 cause certain developmental and degenerative conditions. Scientists have now revealed the structure of the portion of the SMCHD1 protein that is crucial to its function in 'switching off' genes. Inherited mutations in this part of SMCHD1 have been linked to a developmental disorder and a form of muscular dystrophy.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616155955.htm

Open-source machine learning tool connects drug targets with adverse reactions

Scientists develop AI-based tool to predict adverse drug events. Such events are responsible for some 2 million U.S. hospitalizations per year. The free, open-source system could enable safer drug design, optimize drug safety.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200618073536.htm

For babies born with a rare immune deficiency, a unique new test to better target care

A new test will enable better management of patients with severe combined immunodeficiency (SCID).

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617145950.htm

Poor sleep significantly linked with teenage depression

Teenagers who experience very poor sleep may be more likely to experience poor mental health in later life, as depressed teens in study slept 30 minutes less per night than other groups.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617194508.htm

5,000 Walmart Pharmacies Join National “Ready, Set, PrEP” HIV Program

Safeway and other Albertsons pharmacies will also participate, allowing uninsured clients to fill PrEP prescriptions at no cost.


from POZ RSS - Categories https://www.cancerhealth.com/article/5000-walmart-pharmacies-join-national-ready-set-prep-hiv-program

Wednesday, June 17, 2020

Discovery allows 3D printing of sensors directly on expanding organs

Mechanical engineers and computer scientists have developed a 3D printing technique that uses motion capture technology, similar to that used in Hollywood movies, to print electronic sensors directly on organs that are expanding and contracting.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617150045.htm

Seeing corneal degeneration in a new light

The molecular changes that lead to Fuchs' endothelial corneal dystrophy (FECD) occur decades before the disease causes blurry vision and other noticeable symptoms in patients, new research shows. This insight into this earliest stage of FECD may eventually lead to new ways of screening for and treating the common condition, which affects an estimated 4 percent of U.S. adults over the age of 40.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617174809.htm

RNA structures by the thousands

Researchers have developed a new method to determine the structures of all RNA molecules in a bacterial cell at once. In the past, this had to be done individually for each molecule. Besides their exact composition, their structure is crucial for the function of the RNAs. The team has now described the new high-throughput structure mapping method.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617145959.htm

Researchers map out intricate processes that activate key brain molecule

For the first time, scientists have revealed the steps needed to turn on a receptor that helps regulate neuron firing. The findings might help researchers understand and someday treat addiction, psychosis and other neuropsychological diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617150017.htm

Centenarian study suggests living environment may be key to longevity

Where you live has a significant impact on the likelihood that you will reach centenarian age, suggests a new study. New research suggests that people who live in highly walkable, mixed-age communities may be more likely to live to their 100th birthday.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617145256.htm

Detecting antibodies with glowing proteins, thread and a smartphone

To defend the body, the immune system makes proteins known as antibodies that latch onto the perceived threat, be it HIV, the new coronavirus or, as is the case in autoimmune disease, part of the body itself. In a new proof-of-concept study, researchers describe a new system for detecting antibodies within a pinprick of blood within minutes, using an unlikely combination of cotton thread, glowing proteins and a smartphone camera. 

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617121451.htm

Microbes might manage your cholesterol

Researchers discover a link between human blood cholesterol levels and a gene in the microbiome that could one day help people manage their cholesterol through diet, probiotics, or entirely new types of treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617121511.htm

Light-activated 'CRISPR' triggers precision gene editing and super-fast DNA repair

In a series of experiments using human cancer cell lines, scientists say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617121500.htm

Liver perfusion could save 7 in 10 rejected donor livers

A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617102441.htm

A sugar hit to help destroy cancer cells

Like any cells in the body, cancer cells need sugar ­-- namely glucose -- to fuel cell proliferation and growth. However, researchers have unlocked a weakness in a common type of cancer cell: sugar inflexibility. That is, when cancer cells are exposed to a different type of sugar - galactose - the cells can't adapt, and will die.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617100430.htm

Oral antibiotics work, shorten hospital stays for IV drug users with infections

A combination of IV and oral antibiotics can effectively treat invasive infections in people who inject illicit drugs, according to a new study. The findings mean that patients who do not wish to stay in the hospital for weeks of IV antibiotic treatment can leave and complete taking their prescribed antibiotics at home.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617100428.htm

New nanoparticle drug combination for atherosclerosis

Physicochemical cargo-switching nanoparticles (CSNP) can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617100422.htm

A fair reward ensures a good memory

By deciphering the neural dialogue between the brain's reward and memory networks, a new study demonstrates that the lasting positive effect of a reward on the ability of individuals to retain a variety of information.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617100418.htm

Young people with early psychosis may not require antipsychotic medications to recover

Researchers have found that some young people with early stage first episode psychosis (FEP) can experience reduced symptoms and improve functioning without antipsychotic medication when they are provided with psychological interventions and comprehensive case management.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617091003.htm

Half of the world's population exposed to increasing air pollution

Half of the world's population is exposed to increasing air pollution, new research has shown.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617090958.htm

Nanosponges could intercept coronavirus infection

Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200617090950.htm

Hurricane season combined with COVID-19 pandemic could create perfect storm

When extreme climate conditions interact with stressors to social systems, such as the COVID-19 pandemic, the consequences could be severe unless experts from diverse backgrounds work together to develop comprehensive solutions to combat their negative impacts.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616113930.htm

Endogenous insulin production is preserved in Type 1 diabetes with anti-TNF drug

A study found that a drug called golimumab preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616113906.htm

Irregular findings common in knees of young competitive alpine skiers

Bony lesions on the lower part of the thigh bone near the knee are a common but benign finding on MRI in young alpine skiers and should not be confused with more serious conditions, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616100822.htm

Two new, powerful small molecules may be able to kill cancers that other therapies can't

Scientists have identified and developed two potent small molecules that appear to suppress tumor growth in multiple cancers even when other treatments cease to work, possibly due to the development of drug resistance. Called CS1 and CS2, these cancer inhibitor compounds are part of a protein known as ''fat mass and obesity-associated protein.'' This FTO protein plays a critical role in cancer development and progression, primarily because it regulates cancer stem cells and immune evasion.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616100815.htm

Exercise offers 'profound' benefits for Friedreich's ataxia, research suggests

Well-timed exercise programs may slow the progression of Friedreich's ataxia, which robs patients of their ability to walk, new research suggests.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616100811.htm

New discovery paves way for next generation malaria vaccine

New findings pave the way for a novel, next generation genetically attenuated parasite (GAP) vaccine against the deadliest form of malaria in humans.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616100808.htm

60 minutes of endurance training is enough to shift body clock in mice

New research shows that just one 60 minutes bout of exercise shifted the muscle clocks of mice by around an hour in either direction. If this research is replicated in humans, it makes a case for prescribing exercise for night-shift workers and for treating diseases like heart disease, both of which can result in disrupted clocks throughout the body.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615212715.htm

Encouraging HIV Data Out of Iowa

Viral suppression rates, U=U and sustained drops in new HIV cases


from POZ RSS - Categories https://www.cancerhealth.com/article/encouraging-hiv-data-iowa

Tuesday, June 16, 2020

Persistent DNA damage in the placenta affects pregnancy outcomes

Scientists have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome. People with this rare genetic disorder often harbor mutations in cohesins, ring-like proteins that help DNA organize and repair itself.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616113925.htm

Study in Philadelphia links growth in tree canopy to decrease in human mortality

Increased tree canopy or green space could decrease morbidity and mortality for urban populations - particularly in areas with lower socioeconomic status where existing tree canopies tend to be the lowest.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616135820.htm

Virus co-opts immune protein to avoid antiviral defences

By discovering a trick the hepatitis C virus uses to evade the immune system, scientists have identified a new antiviral defence system that could be used to treat many virus infections, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616135808.htm

Primitive stem cells point to new bone grafts for stubborn-to-heal fractures

Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting. Researchers have now created superior bone grafts using primitive stem cells. They found that these cells help create very fertile scaffolds needed for bone to regenerate at the site of repair.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616135752.htm

A coordinated COVID-19 response helped western Washington state 'flatten the curve'

A regional coalition-guided multifaceted approach engaged health systems, long-term care facilities, state and local governments, and organizations to rapidly respond to the outbreak.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616135756.htm

TERAVOLT registry tracks outcomes among thoracic cancer patients sickened by COVID-19

New data from TERAVOLT, a global consortium that tracks outcomes of people with thoracic cancers affected by COVID-19, offers clues as to why they experienced a high death rate of 33 percent when the coronavirus swept across Europe.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616135754.htm

Researchers identify potent antibody cocktail to treat COVID-19

Researchers evaluated several human antibodies to determine the most potent combination to be mixed in a cocktail and used as a promising anti-viral therapy against the virus that causes COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616135739.htm

Following a variety of healthy eating patterns associated with lower heart disease risk

Greater adherence to a variety of healthy eating patterns was associated with a lower risk of cardiovascular disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140902.htm

Could the cure for IBD be inside your mouth?

A new collaborative study reveals that inflammatory bowel disease (IBD) may be the latest condition made worse by poor oral health via a clash between the mouth and gut microbiomes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616113927.htm

Brain research sheds light on the molecular mechanisms of depression

A new study reveals how symptoms indicating depression and anxiety are linked to brain function changes already in healthy individuals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616113920.htm

Depression associated with greater risk of cardiovascular disease

A new study provides further evidence of the link between depressive symptoms and an increased risk of heart disease and early death.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616100817.htm

Susceptibility to carcinogens varies due to genetics

A new study looks into how and why certain individuals develop cancer and others do not.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616100825.htm

Working in the sun: Heating of the head may markedly affect safety and performance

Prolonged exposure of the head to strong sunlight significantly impairs cognitively dominated functions and coordination of complex motor tasks shows a new study. This may have important implications for work safety and productivity.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616083404.htm

Wearable patch may provide new treatment option for skin cancer

Innovators have created a novel wearable patch to provide an improved treatment experience for people with melanoma. The researchers developed a novel wearable patch with fully miniaturized needles, enabling unobtrusive drug delivery through the skin for the management of skin cancers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616083349.htm

Scientists propose explanation for baffling form of childhood OCD

Scientists may have found a cause for the sudden onset of obsessive-compulsive disorder (OCD) in some children, they report. Pediatric autoimmune neuropsychiatric disorders, or PANDAS, were first proposed in the 1990s. Thought to be triggered by streptococcal infections, they account for an unknown portion of youth OCD cases. But the biology underpinning this disorder has baffled scientists.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200616083222.htm

5 Ways the Criminal Justice System Can Meet the Challenges of COVID-19

HIV criminalization experts convened attorneys and stakeholders to propose public health guidelines.


from POZ RSS - Categories https://www.cancerhealth.com/article/5-ways-criminal-justice-system-can-meet-challenges-covid19

Monday, June 15, 2020

Calling for nursing support amid COVID-19 pandemic

In a new editorial, researchers call for rapid policy reform and investment in nurses and nursing in order to leverage the skills of this global workforce.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615184154.htm

COVID-19 pandemic could decimate outdoor environmental, science education programs

A survey of 1,000 outdoor education programs nationwide finds that nearly two-thirds are in danger of folding because of the COVID-19 pandemic. Such programs connect youth with the world around them and teach about nature, with documented academic, health and social benefits. But most programs are conducted by residential outdoor science schools, nature centers, parks and zoos, not in traditional classrooms. The loss will be felt disproportionately by students of color and low-income students.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140919.htm

Maternal transmission of COVID-19 to baby during pregnancy is uncommon, study finds

Transmission of COVID-19 from mother to baby during pregnancy is uncommon, and the rate of infection is no greater when the baby is born vaginally, breastfed or allowed contact with the mother, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140859.htm

Researchers develop model to predict likelihood of testing positive for COVID-19, disease outcomes

A new risk prediction model for healthcare providers can forecast an individual patient's likelihood of testing positive for COVID-19 as well as their outcomes from the disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140852.htm

Combination drug treatments for COVID-19 show promise in cell culture tests

Researchers have established a cell culture that allows them to test antibody-laden plasma, drugs and drug combinations in the laboratory. A screen of 136 safe-in-human antiviral drugs and identified six promising candidates. One combination of two drugs was so effective that researchers hope others can begin clinical trials on the drugs now.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140845.htm

COVID-19 hospitalizations could mean significant out-of-pocket medical costs for many Americans

If past hospitalizations for pneumonia and other respiratory illnesses are any guide, many Americans could face high out-of-pocket medical costs for COVID-19 hospitalizations.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140833.htm

Study examines the prevalence of COVID-19 infections in pregnant women

A new paper reports on the prevalence of infections with the SARS-CoV-2 virus in women admitted to labor and delivery units in several Boston hospitals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140826.htm

Molecules that reduce 'bad' gut bacteria reverse narrowing of arteries in animal study

Scientists have developed molecules that can remodel the bacterial population of intestines to a healthier state. They also have shown -- through experiments in mice -- that this approach reduces cholesterol levels and strongly inhibits the thickened-artery condition known as atherosclerosis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140921.htm

Tuberculosis vaccine strengthens immune system

A tuberculosis vaccine developed 100 years ago also makes vaccinated persons less susceptible to other infections. While this effect has been recognized for a long time, it is not known what causes it.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140855.htm

Brothers in arms: The brain and its blood vessels

The brain and its surrounding blood vessels exist in a close relationship. Researchers have discovered how cells of the blood vessels sense the metabolic condition of the brain and alter vascular function in response. The result could be important for patients with neurodegenerative disorders such as Alzheimer's because the onset of these age-related diseases coincides with vascular defects and breakdown of vascular function in the brain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140850.htm

Immune properties in ancient DNA found in isolated villages might benefit humanity today

Could remnants of DNA from a now extinct human subspecies known as the Denisovans help boost the immune functions of modern humans? An international study represents the first characterizations of genes in the DNA of healthy individuals from geographically and genetically distinct populations in Indonesia.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140838.htm

Researchers uncover drivers of healthy gut maintenance

Researchers have found two genes that regulate the differentiation of stem cells in the small intestine, offering valuable insight into how the body develops and maintains a healthy gut.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140821.htm

Neurons can shift how they process information about motion

New research indicates some neurons can shift to process information about movement depending on the brain's current frame of reference. The findings may have implications for developing future prosthetics and for understanding some brain disorders.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615140818.htm

Federal Health Care Rule Tries to Roll Back LGBT Protections

The new rule could allow insurance plans to limit or deny coverage and to also discriminate against people living with HIV.


from POZ RSS - Categories https://www.cancerhealth.com/article/federal-health-care-rule-tries-roll-back-lgbt-protections

Improved gut microbiota with cholesterol-lowering medication

There is a clear link between improved gut microbiota and one of our most common cholesterol-lowering drug groups: statins.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115816.htm

Tuberculosis spread from animals to humans may be greater than previously thought

The number of human tuberculosis (TB) cases that are due to transmission from animals, as opposed to human-to-human transmission, may be much higher than previously estimated, according to an international team of researchers. The results could have implications for epidemiological studies and public health interventions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115814.htm

More and safer heart transplants could become possible with new heart box

A donated heart can now be transported and preserved for longer than what has previously been possible. The new method, which consists of a specially designed heart box, was used for a transplant for the first time as early as the summer of 2017. Now it has been evaluated in a first clinical study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115752.htm

Vegetarians tend to be slimmer and less extroverted than meat eaters, study finds

The less animal products someone consumes, the lower his body mass index on average and the less he tends to be extroverted. A connection with depressive moods as other studies had found could not be confirmed.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115748.htm

AI reduces 'communication gap' for nonverbal people by as much as half

Researchers have used artificial intelligence to reduce the 'communication gap' for nonverbal people with motor disabilities who rely on computers to converse with others.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115729.htm

3D X-ray reveals secrets from inside bones

Researchers have uncovered a previously unknown substructure in bone tissue using a new X-ray technique to produce 3D images of the internal structure of bones. The discovery potentially questions fundamentally a number of the models of bone tissue and the mechanical properties of bones that, among other things, is used to describe the process of bone formation.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115727.htm

Multi-ethnic study suggests vitamin K may offer protective health benefits in older age

A new, multi-ethnic study found adults aged 54-76 with low circulating vitamin K levels were more likely to die within 13 years compared to those with adequate levels, suggesting vitamin K may offer protective health benefits as we age.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115725.htm

Diluting blood plasma rejuvenates tissue, reverses aging in mice

A new study reveals that replacing half of the blood plasma with a mixture of saline and albumin reverses signs of aging and rejuvenates muscle, brain and liver tissue in old mice. The research team is currently finalizing clinical trials to determine if a modified plasma exchange in humans could be used to treat age-associated diseases and improve the overall health of older people.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115724.htm

Role of lipid rafts in virus infiltration

New research sheds light on how and why the cell membrane forms and grows lipid rafts triggered by ligand-receptor activity. The work could lead to new strategies and innovative approaches to prevent or fight the action of the virus through the integration of biomedical and engineering knowledge.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615115719.htm

Muscles support a strong immune system

In the fight against cancer or chronic infections, the immune system must be active over long periods of time. However, in the long run, the immune defense system often becomes exhausted. Scientists have now found initial evidence in mice that skeletal muscles help to keep the immune system functional in chronic diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615092747.htm

Significant parental hesitancy about routine childhood and influenza vaccines

A national study measuring parental attitudes toward vaccinations found 6.1% were hesitant about routine childhood immunizations while nearly 26% were hesitant about the influenza vaccine.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615092740.htm

Artificial intelligence estimates peoples' ages

Wrinkles, furrows, spots: a person's aging process is accompanied by tell-tale signs on their face. Researchers have developed an algorithm that interprets these features very reliably.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615100945.htm

Exposure to air pollution impairs cellular energy metabolism

Exposure to air particulate matter impairs the metabolism of olfactory mucosal cells, according to a recent study. The results can contribute to a better understanding of how air pollutants may harm brain health, as the olfactory mucosa can act as a key pathway to the brain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615100929.htm

Study demonstrates feasibility of hologram technology in liver tumor ablation

Data from one of the first clinical uses of augmented reality guidance with electromagnetically tracked tools shows that the technology may help doctors quickly, safely, and accurately deliver targeted liver cancer treatments, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615092737.htm

House-call model tapping interventional radiology improves outcomes and access to care

Interventional radiologists participating in a collaborative house call model in rural Indiana helped reduce emergency department use by 77% and hospital readmissions by 50 percent for nearly 1,000 elderly homebound patients with chronic illnesses, according to a new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615092735.htm

Novel treatment for mesothelioma shows promise for patients

A novel treatment for advanced mesothelioma is safe and effective and may improve the quality of life for patients who have few treatment options, according to new research. Transarterial chemoperfusion treatment for malignant pleural mesothelioma (MPM) comes with minimal side effects and shows promise for extending the lives of patients who have limited or no remaining treatment options.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200615092733.htm

Sunday, June 14, 2020

Siblings of infants who have died suddenly and unexpectedly at 10-fold risk of same death

The siblings of infants who have died suddenly and unexpectedly run 10 times the risk of dying in the same way, indicates a long term analysis of monitoring data.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200611183923.htm

Saturday, June 13, 2020

Protecting scientific diversity

The COVID-19 pandemic means that scientists face great challenges because they have to reorient, interrupt or even cancel research and teaching. A team of international scientists are highlighting the precarious situation of many scientists and calling for a collective effort by the scientific community, especially from its leadership, to protect decades of effort to build an inclusive scientific community.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612111344.htm

Only 1 in 3 COVID-19 research authors are women, and even fewer are senior authors

Women make up only a third of all authors who have published research on COVID-19 since the beginning of the pandemic in January this year, and even fewer of them are senior authors on these papers, suggests a recent analysis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200611183927.htm

Survey suggests the importance of clearly communicating coronavirus risk, behaviors

A newly published analysis of March survey data sheds light on our understanding of how perceptions of the virus impact behavior, finding individuals who perceive greater risk from COVID-19 were more likely to engage in protective behaviors like hand-washing and social distancing.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200611183910.htm

A protein that helps to fight viruses can also block lung damage repair

Researchers have found that a protein which is initially helpful in the body's immune response to a virus, can later interfere with the repair of lung tissue. The work highlights the need for careful consideration regarding the use of this protein to treat viruses, including coronavirus.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200611152453.htm

Face masks critical in preventing spread of COVID-19

A study has found that not wearing a face mask dramatically increases a person's chances of being infected by the COVID-19 virus.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612172200.htm

Cytokine implicated in HLH treatment resistance

Research sheds light on cytokine storm syndromes and how ruxolitinib may benefit patients with hemophagocytic lymphohistiocytosis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612111421.htm

COVID-19: Tradeoffs between economics and public health

A new study uses a variety of data on consumer and business activity to tackle that question, measuring 26 types of businesses by both their usefulness and risk. Vital forms of commerce that are relatively uncrowded fare the best in the study; less significant types of businesses that generate crowds perform worse. The results can help inform the policy decisions of government officials during the ongoing pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200611183930.htm

People who eat a late dinner may gain weight

Eating a late dinner may contribute to weight gain and high blood sugar, according to a small study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200611094138.htm

Scientists uncover immune cells that may lower airway allergy and asthma risk

Scientists offer a clue to why non-allergic people don't have a strong reaction to house dust mites. They've uncovered a previously unknown subset of T cells that may control allergic immune reactions and asthma from ever developing in response to house dust mites -- and other possible allergens.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612172234.htm

Researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies

A new study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612171238.htm

Fuel walking and cycling with low carbon diets

Walking and cycling have many benefits and help reduce greenhouse gas emissions, but researchers say we need to think about what people eat to fuel their walking and cycling.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612111432.htm

Repairing thousands of disease-causing mutations

Researchers have created a new searchable library of base editors -- an especially efficient and precise kind of genetic corrector. Using experimental data from editing more than 38,000 target sites in cells with 11 of the most popular base editors (BEs), they created a machine learning model that accurately predicts base editing outcomes. Called BE-Hive, the library is free and open to the public.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612111419.htm

Unlocking PNA's superpowers for self-assembling nanostructures

Researchers have developed a method for self-assembling nanostructures with gamma-modified peptide nucleic acid, a synthetic mimic of DNA. The process has the potential to impact nanomanufacturing and future biomedical technologies like targeted diagnostics and drug delivery.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612111417.htm

Study identifies mechanism affecting X chromosome that could lead to new disease therapies

Learning how to inactivate and reactivate an X chromosome would have important implications for medicine. A notable category of beneficiaries could be people with certain congenital diseases known as X-linked disorders, which are caused by mutations in genes on the X chromosome.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612111416.htm

Silicones may lead to cell death

Silicone molecules from breast implants can initiate processes in human cells that lead to cell death, according to new research

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/06/200612111353.htm