Scientists regenerate neurons in mice with spinal cord injury and optic nerve damage

Each year thousands of patients face life-long losses in sensation and motor function from spinal cord injury and related conditions in which axons are badly damaged or severed. New research in mice shows, however, that gains in functional recovery from these injuries may be possible, thanks to a molecule known as Lin28, which regulates cell growth.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430113041.htm

Better understanding of nature's nanomachines may help in design of future drugs

Many of the drugs and medicines that we rely on today are natural products taken from microbes like bacteria and fungi. Within these microbes, the drugs are made by tiny natural machines known as nonribosomal peptide synthetases (NRPSs). A research team has gained a better understanding of the structures of NRPSs and the processes by which they work. This improved understanding of NRPSs could potentially lead to the creation of new potent antibiotics, immunosuppressants and other modern drugs.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430150224.htm

High cost of cancer drugs not always justified

Do high prices of some cancer medicines have a higher benefit than those drugs with lower prices? An international study has concluded that, in general, there is no correlation between costs of a cancer drugs and their clinical benefit. The researchers are therefore calling for the clinical benefit of drugs to be better reflected in pricing.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430191313.htm

Mind-controlled arm prostheses that 'feel' are now a part of everyday life

For the first time, people with arm amputations can experience sensations of touch in a mind-controlled arm prosthesis that they use in everyday life. A study reports on three Swedish patients who have lived, for several years, with this new technology -- one of the world's most integrated interfaces between human and machine.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430110321.htm

A new way to accurately estimate COVID-19 death toll

A new mathematical model has been created to estimate the death toll linked to the COVID-19 pandemic in the United States and could be used around the world.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430091256.htm

Clinicians warn of the dangers of equating COVID-19 with high altitude pulmonary edema

Early reports of COVID-19 symptoms and the compelling need to quickly identify treatment options and curb the growing number of critically ill patients have led to erroneous and potentially dangerous comparisons between COVID-19 and other respiratory diseases like high altitude pulmonary edema, or HAPE.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430091251.htm

Researchers offer ways to address life under COVID-19

Researchers have outlined ways to manage different facets of life under the spread of the COVID-19 virus, ranging from how we can combat racially driven bias and fake news to how we can increase cooperation and better manage stress.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430113048.htm

Blood clotting a significant cause of death in patients with COVID-19

A new study has found that Irish patients admitted to hospital with severe COVID-19 infection are experiencing abnormal blood clotting that contributes to death in some patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430113015.htm

The story of three African slaves during Spanish colonialism, as told by their bones

Scientists tell the story of three 16th century African slaves identified from a mass burial site in Mexico City. Using a combination of genetic, osteological, and isotope analyses, the scientists determined from where in Africa they were likely captured, the physical hardships they experienced as slaves, and what novel pathogens they may have carried with them across the Atlantic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430113008.htm

Narcan for Reversing Drug Overdoses Now Available by Mail

This is one of many ways that people who use drugs can engage in harm reduction during the coronavirus pandemic.


from POZ RSS - Categories https://www.cancerhealth.com/article/narcan-reversing-drug-overdoses-now-available-mail

Another Reason HIV Rates Might Increase in the Era of COVID-19

We’ve reported on STI clinics closing, but harm reduction advocates are also raising alarms—and trying to reach those most vulnerable.


from POZ RSS - Categories https://www.cancerhealth.com/article/another-reason-hiv-rates-might-increase-era-covid19

Reduced obesity for weighted-vest wearers

Scientists have found a new method of reducing human body weight and fat mass using weighted vests. The new study indicates that there is something comparable to built-in bathroom scales that contributes to keeping our body weight and, by the same token, fat mass constant.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430091301.htm

Double bubbles pierce with less trouble

Two microscopic bubbles penetrate soft materials better than one, concludes a new study by engineers. Optical cavitation uses a laser to form bubbles in a liquid that expand rapidly then collapse. The new article shows two bubbles produce long, fine jets that penetrate far enough with only five pulses to make cavitation potentially suitable for transfection or needle-free injections.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200430101451.htm

Protein mystery of three brain diseases unraveled

The accumulation of one particular protein in the brain is at the basis of three very different age-related conditions. Until recently, nobody understood how this was possible. Research now reveals that the shape of the protein determines the clinical picture.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429201706.htm

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

As physicians and families know too well, though Alzheimer's disease has been intensely studied for decades, too much is still not known about molecular processes in the brain that cause it. Now researchers say new insights from analytic theory and molecular simulation techniques offer a better understanding of amyloid fibril growth and brain pathology.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429191906.htm

Ultra-precision nano-sensor could detect iron disorders

Scientists have developed a hypersensitive nano-sensor to detect harmful 'free' iron disorders. The test could lead to earlier, more accurate disease diagnosis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105850.htm

COVID-19 crisis: Millions of US workers at risk of infections on the job

New research shows that 14.4 million workers face exposure to infection once a week and 26.7 million at least once a month in the workplace, pointing to an important population needing protection as the novel coronavirus disease, COVID-19, continues to break out across the US.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105834.htm

Novel imaging application illuminates processes in cancer, COVID-19

Medical images for a wide range of diseases can be more easily viewed, compared, and analyzed using a breakthrough open source web-based imaging platform developed by Massachusetts General Hospital (MGH) and collaborating researchers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429155658.htm

Navigating the clean energy transition during the COVID-19 crisis

In a Commentary published April 29 in the journal Joule, energy and climate policy researchers in Switzerland and Germany provide a framework for responsibly and meaningfully integrating policies supporting the clean energy transition into the COVID-19 response in the weeks, months, and years to come.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429152825.htm

Implant-free optogenetics minimizes brain damage during neuronal stimulation

A minimally invasive optogenetic technique that does not require brain implants successfully manipulated the activity of neurons in mice and monkeys, researchers report. The researchers first genetically engineered neurons to produce a newly developed, extremely light-sensitive protein called SOUL. They then demonstrated that it is possible to shine light through the skull to alter neuronal responses throughout the entire mouse brain, and to reach superficial regions of the macaque brain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429111141.htm

Bone proteomics could reveal how long a corpse has been underwater

When a dead body is found, one of the first things a forensic pathologist tries to do is estimate the time of death. There are several ways to do this, including measuring body temperature or observing insect activity, but these methods don't always work for corpses found in water. Now, researchers are reporting a mouse study showing that certain proteins in bones could be used for this determination.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105916.htm

Feeling burned out? The contributors could be more related to depression than you think

Researchers found that similar factors cause both medical intern burnout and depression. These findings can be used to identify and treat burnout as well as mitigate the risk of burnout by modifying workplace factors.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105914.htm

Model can predict hospital resilience for natural disasters, pandemics

Researchers have created a modeling tool that could help cities understand the full functionality and recovery of a healthcare system in the wake of a natural disaster. The model has wider implications for use in pandemics.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105905.htm

Molecular switch plays crucial role in learning from negative experiences

Neurobiologists have discovered how the signalling molecule Neuromedin U plays a crucial role in our learning process. The protein allows the brain to recall negative memories and, as such, learn from the past.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105901.htm

Arteries respond in opposite ways for males and females

A protein known to expand blood vessels -- key to controlling conditions like high blood pressure -- actually has different functions in males and females, new UC Davis Health research shows. Conducted using arterial cells from mice, the study is the first to identify sex-based distinctions in how the protein -- Kv2.1 -- works.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105840.htm

Schizophrenia related to abnormal fatty metabolism in the brain

Researchers have discovered a deficiency in the brains of people with schizophrenia that could lead to the development of new drug therapies. A postmortem comparison revealed that schizophrenia was associated with lower than normal levels of S1P, a type of fatty molecule found in the white matter of the brain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428225419.htm

Major trial shows breast cancer drug can hit prostate cancer Achilles heel

A drug already licensed for the treatment of breast and ovarian cancers is more effective than targeted hormone therapy at keeping cancer in check in some men with advanced prostate cancer, a major clinical trial reports. Olaparib, a pill lacking the side effects of chemotherapy, can target an Achilles heel in prostate cancers with a weakness in their ability to repair damaged DNA.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428170629.htm

New insights linking cell division to cancer

Scientists are extending our understanding of the intricate process of cell division.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429134013.htm

Researchers measure cancer cell mechanics in living animals using nanoparticles

Researchers developed a first-of-its-kind nanoparticle-based in vivo imaging technique may one day be used to help diagnose and even treat cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429134008.htm

First study of multicancer blood test to screen for cancer guide intervention

Results from a first-of-its-kind study of a multicancer blood test in more than 9,900 women with no evidence or history of cancer showed the liquid biopsy test safely detected 26 undiagnosed cancers, enabling potentially curative treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429133958.htm

Alzheimer’s gene triggers early breakdowns in blood-brain barrier, predicting cognitive decline

Although scientists have long known APOE4 is a leading risk factor for Alzheimer's disease, they were unsure how exactly it drives a decline in memory. Scientists believe they have now found an answer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429133947.htm

Study accurately tracks COVID-19 spread with big data

Researchers have developed a new method to accurately track the spread of COVID-19 using population flow data, and establishing a new risk assessment model to identify high-risk locales of COVID-19 at an early stage, which serves as a valuable toolkit to public health experts and policy makers in implementing infectious disease control during new outbreaks.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429133940.htm

A milder hair dye based on synthetic melanin

With the coronavirus pandemic temporarily shuttering hair salons, many clients are appreciating, and missing, the ability of hair dye to cover up grays or touch up roots. However, frequent coloring, whether done at a salon or at home, can damage hair and might pose health risks from potentially cancer-causing dye components. Now, researchers have developed a process to dye hair with synthetic melanin under milder conditions than traditional hair dyes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429092321.htm

Sensitive new test detects antibodies against SARS-CoV-2 in only 10 minutes

A proof-of-concept study describes a quick, sensitive test for antibodies against the coronavirus in human blood. The test could help doctors track a person's exposure to the disease, as well as confirm suspected COVID-19 cases that tested negative by other methods.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429144914.htm

Stark disparities in COVID-19 hospitalization and death rates among New York

Researchers found that COVID-19 hospitalization and death rates varied across New York City boroughs. The Bronx -- with the highest proportion of racial/ethnic minorities, the most poverty, and lowest educational attainment -- had higher rates of hospitalization and death related to COVID-19 than all other boroughs. These rates were lowest in affluent Manhattan, comprised of a predominately white population. COVID-19 deaths per 100,000 persons was nearly two times greater in the Bronx than in Manhattan.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429134011.htm

Offspring may inherit legacy of their father's Toxoplasma infection

Researchers have revealed for the first time that males infected with the Toxoplasma parasite can impact their offspring's brain health and behavior. Studying mice infected with the common parasite Toxoplasma, the team discovered that sperm of infected fathers carried an altered 'epigenetic' signature which impacted the brains of resulting offspring. Molecules in the sperm called 'small RNA' appeared to influence the offspring's brain development and behavior.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105909.htm

Link identified between dietary selenium and outcome of COVID-19 disease

Researchers have identified a link between the COVID-19 cure rate and regional selenium status in China.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429105907.htm

NIH clinical trial shows remdesivir accelerates recovery from advanced COVID-19

Hospitalized patients with advanced COVID-19 and lung involvement who received remdesivir recovered faster than similar patients who received placebo, according to a preliminary data analysis from a randomized, controlled trial involving 1063 patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429141311.htm

First randomized trial of remdesivir suggests antiviral drug is not associated with significant clinical benefits, more research needed

Treatment with the antiviral drug remdesivir does not speed recovery from COVID-19 compared with placebo in hospitalized patients who are critically ill, according to the first randomized trial of its kind involving 237 adults from 10 hospitals in Wuhan, China.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429134020.htm

To prevent antimicrobial resistance, vaccinate the world's kids

Childhood vaccination may be a powerful tool in the fight against antimicrobial resistance in low- and middle-income countries, finds a new analysis. The study found that immunization with two common vaccines -- the pneumococcal conjugate and rotavirus vaccines -- significantly reduces the rates of acute respiratory infections and diarrhea among small children in these settings. And, with fewer children getting sick or severely sick, fewer are receiving antibiotic treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429133955.htm

Simple 'sniff test' reliably predicts recovery of severely brain injured patients

The ability to detect smells predicts recovery and long-term survival in patients who have suffered severe brain injury, a new study has found. A simple, inexpensive 'sniff test' could help doctors to accurately diagnose and determine treatment plans for patients with disorders of consciousness.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429111146.htm

Researchers help give robotic arms a steady hand for surgeries

Steady hands and uninterrupted, sharp vision are critical when performing surgery on delicate structures like the brain or hair-thin blood vessels. While surgical cameras have improved what surgeons see during operative procedures, the 'steady hand' remains to be enhanced -- new surgical technologies, including sophisticated surgeon-guided robotic hands, cannot prevent accidental injuries when operating close to fragile tissue.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429134018.htm

HIV2020 Global Conference Will Now Take Place Online

Free virtual sessions will run from June through October.


from POZ RSS - Categories https://www.cancerhealth.com/article/hiv2020-global-conference-will-now-take-place-online

Higher thrombus risk in men with obesity in adolescence

Men with a history of obesity in their late teens are, in adult life are more at risk of a blood clot (thrombus) in a leg or lung, according to a new study. The risk rises successively and is highest in those who were severely obese in adolescence.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200429075848.htm

Scientists recreate DNA damage caused by toxins from smoking

Researchers have recreated how toxins from smoking cause unique patterns of DNA damage. The discovery could help scientists better understand the cause of bladder cancer and the link to smoking. The causes of bladder cancer remain largely unknown, however smoking is seen as the main risk factor for the disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428225426.htm

Beta cells from stem cells: Potential for cell replacement therapy

Researchers have developed an improved pluripotent stem cell differentiation protocol to generate beta cells in vitro with superior glucose response and insulin secretion -- a major step towards beta cell replacement therapy.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125132.htm

Open access hardware and 3D printing can help tackle demand for health supplies

Free open source hardware and 3D printing could help to alleviate the burden of Covid-19 on global health systems, according to scientists.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125211.htm

Parkinson's disease may start in the gut

Researchers have mapped out the cell types behind various brain disorders. The findings offer a roadmap for the development of new therapies to target neurological and psychiatric disorders. One interesting finding was that cells from the gut's nervous system are involved in Parkinson's disease, indicating that the disease may start there.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125152.htm

Childhood obesity and high blood pressure warn of future heart disease

A large study in adolescents and children, some as young as 3 years of age, shows a link between obesity, high blood pressure, and later damage to blood vessels.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428112525.htm

New staining technique visualizes whole organs and bodies

A research team has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology. The study details how the new technique can be used to stain tissue and label cells in mouse brains, human brains, and whole marmoset bodies. This technique will allow detailed anatomical analysis and whole-organ comparisons between species at the cellular level.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427091643.htm

Artificial intelligence could serve as backup to radiologists' eyes

Deploying artificial intelligence could help radiologists to more accurately classify lung diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427091641.htm

R.I.P. Deloris Dockrey, HIV Activist and Leader Lost to COVID-19

A fighter for other women living with HIV, she worked at the Hyacinth Clinic in Newark, New Jersey.


from POZ RSS - Categories https://www.cancerhealth.com/article/rip-deloris-dockrey-hiv-activist-leader-lost-covid19

Variation in how side effects are reported clouds drug safety

A new study finds significant variation in how drug side effects are reported, potentially making some drugs seem safer or less safe than they really are.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428154054.htm

Agricultural pickers in US to see unsafely hot workdays double by 2050

Temperature increases by 2050 and 2100 in U.S. counties where crops are grown will double, then triple the number of unsafe workdays. The study also looks at strategies the industry could adopt to protect workers' health.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428131716.htm

Correlations in COVID-19 growth point to universal strategies for slowing spread

Models drawing on chaos theory find growth in nine countries conforms to a power law curve and highlight the value of strict social distancing and testing policies.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428112535.htm

Urban slums are uniquely vulnerable to COVID-19: Here's how to help

Government-enforced social isolation can be devastating for the nearly 1 billion people around the globe currently dwelling in urban slums, where physical space is scarce and many rely on daily wage labor for survival. A new report, authored by a team of public health experts and epidemiologists working in collaboration with community leaders and non-governmental organizations, provides eight urgent recommendations for reducing the impact of COVID-19 on people living in poverty.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428084701.htm

Making sense of the viral multiverse

Researchers propose a new classification system, capable of situating coronaviruses like SARS-CoV-2 within the enormous web of viruses across the planet, known as the virosphere.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427184134.htm

Contact tracing and isolation key to controlling SARS-CoV2 in Shenzhen, report finds

Contact tracing to rapidly isolate people who could be infected with coronavirus disease 2019 (COVID-19) reduced the length of time people were infectious in the community over 4 weeks (from 14 January to 12 February 2020) in Shenzhen, China, according to newly published results from 391 cases and 1,286 of their close contacts.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427184126.htm

Work-related stress linked to increased risk for peripheral artery disease

People who reported work-related stress were more likely to be hospitalized for treatment of peripheral artery disease compared to those who did not report work-related stress. Work-related stress, or job strain, refers to psychological and social stress at work, often from high expectations combined with lower levels of personal control.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428093515.htm

New type of immune cell discovered in breast ducts

Breast cancer researchers have discovered a new type of immune cell that helps to keep breast tissue healthy by regulating a vital process within mammary ducts - the sites where milk is produced and transported, but also where most breast cancers arise.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428093512.htm

A child's home environment can impact the risk of developing depression

New research finds that children's rearing environment has a meaningful impact on their risk for major depression later in life, and notes the importance supporting of nurturing environments when children are at risk.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428084705.htm

Experts successfully treat severe case of COVID-19 in 3-week-old infant

In one of the first reported cases of its kind, a 3-week-old infant in critical condition recovered from COVID-19 due to rapid recognition and treatment by physicians from McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428145413.htm

Gut microbes influence how rat brains react to opioids

Antibiotic treatment -- which depletes gut microbes -- drastically changes the parts of a rat's brain that are activated during opioid addiction and withdrawal.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427140505.htm

How the heart affects our perception

When we encounter a dangerous situation, signals from the brain make sure that the heart beats faster. When we relax the heart slows down. But the heartbeat also affects the brain but the underlying mechanisms are unclear. Researchers have now identified two mechanisms underpinning how the heart influences our perception, the brain, and how these mechanisms differ between individuals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428131707.htm

Researchers' method holds promise for brain study, better tests for viruses

Researchers have developed a promising method for remotely stimulating activity in deep brain regions, advancing understanding of how molecules act in the brain and paving the way for better cancer treatments and therapies for other diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125145.htm

Light-based deep brain stimulation relieves symptoms of Parkinson's disease

Biomedical engineers have used light-based deep brain stimulation to treat motor dysfunction in an animal model of Parkinson's disease. Succeeding where earlier attempts have failed, the method promises to provide new insights into why deep brain stimulation works and ways in which it can be improved on a patient-by-patient basis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125141.htm

Immune-regulating drug improves gum disease in mice

A drug that has life-extending effects on mice also reverses age-related dental problems in the animals, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428112540.htm

People with brown fat may burn 15% more calories

Short-term cold exposure may help people with brown fat burn 15% more calories than those without, according to a small study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428091504.htm

Smart contact lenses that diagnose and treat diabetes

Medical researchers have develops wireless smart contact lenses for diagnosis and treatment of diabetes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200428091502.htm

ViiV’s $3.7M COVID-19 Fund Will Support HIV Groups and Researchers

Here’s how local community organizations and HIV scientists alike can apply for grants from the HIV health care company.


from POZ RSS - Categories https://www.cancerhealth.com/article/viivs-37m-covid19-fund-will-support-hiv-groups-researchers

No, the New Coronavirus Is Unlikely Sexually Transmitted Via Semen

However, intimate contact can increase the risk of spreading COVID-19 through coughing, sneezing and kissing, experts caution.


from POZ RSS - Categories https://www.cancerhealth.com/article/new-coronavirus-unlikely-sexually-transmitted-via-semen

Coupled magnetic materials show interesting properties for quantum applications

Researchers have uncovered a novel way in which the excitations of magnetic spins in two different thin films can be strongly coupled to each other through their common interface.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125119.htm

New understanding of asthma medicines could improve future treatment

New research has revealed new insights into common asthma aerosol treatments to aid the drug's future improvements which could benefit hundreds of millions of global sufferers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427110141.htm

Antibiotic exposure can 'prime' single-resistant bacteria to become multidrug-resistant

Researchers report that, for a bacterial pathogen already resistant to an antibiotic, prolonged exposure to that antibiotic not only boosted its ability to retain its resistance gene, but also made the pathogen more readily pick up and maintain resistance to a second antibiotic and become a dangerous, multidrug-resistant strain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125213.htm

New tool measures quality of life in people with dementia

University of Queensland researchers say a new tool to measure of the quality of life of people with dementia will result in better targeted care for those living with the condition.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427102548.htm

Smart interventions reduce malaria transmission by 75%

Mass drug administration and vector control can help eliminate malaria. A vector refers to an organism that transmits infection, as mosquitoes infected with parasites transmit malaria to people.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427102546.htm

Scientists unveil how general anesthesia works

The discovery of general anesthetics -- compounds which induce unconsciousness, prevent control of movement and block pain -- helped transform dangerous operations into safe surgery. But scientists still don't understand exactly how general anesthetics work. Now, researchers have revealed how a general anesthetic called isoflurane weakens the transmission of electrical signals between neurons, at junctions called synapses.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427125200.htm

Scientists shed light on action of key tuberculosis drug

A new study has shed fresh light on how a key front-line drug kills the tuberculosis bacterium.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423143038.htm

Herpes virus decoded

The genome of the herpes simplex virus 1 was decoded using new methods. Hundreds of previously unknown gene products were found. The virus causes lip herpes, but can also be life-threatening.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200427091645.htm

It’s a Terrible Time for COVID-19 to Strike HIV, STI and Hepatitis Programs

A survey of local health departments reveals concerning news—and a silver lining.


from POZ RSS - Categories https://www.cancerhealth.com/article/terrible-time-covid19-strike-hiv-sti-hepatitis-programs

Traffic officer protein governs speed of sugar/fat conversion pathway

Scientists have identified a protein sensor that restricts how much sugar and fat our cells convert into energy during periods of starvation. It is possible, the scientists say, that the sensor could be fine-tuned to prompt more sugar and fat conversion in people with metabolic conditions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424150736.htm

Structure of biocatalysts depends on whether they are in cells or test tubes

The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through movable 'hinges.' The shape of enzymes can depend on whether their structure is measured in the test tube or in the living cell. This is what physicochemists discovered about YopO, an enzyme of the plague pathogen.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424132558.htm

Holistic approach best for tackling nonmedical drug use, study finds

Health practitioners are constantly developing new ways to help those with drug and alcohol addictions wean themselves from their substance of choice. Most such programs have limited success, however. A new study finds that interventions that take a multidimensional approach -- tackling the biological, social, environmental and mental health obstacles to overcome while also addressing a person's substance use -- work best for those hoping to stop using drugs.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424132531.htm

Syphilis eludes immune attack by altering a single gene

Shuffling of DNA in a single gene might be why the syphilis bacteria can evade the immune system. The change alters a protein on its cell surface to create a distraction. People can become re-infected several times with syphilis because they can't develop immunity, Untreated syphilis can hide in the body for decades. Genomic findings on these evasive strategies may point to designs for vaccines to outwit syphilis' defenses.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424093604.htm

Boosting the immune system's appetite for cancer

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423174040.htm

Breakthrough discovery in HIV research opens path to new, better therapies

Cells infected with HIV make two forms of the virus's RNA. A new article finds a single nucleotide controls which version of viral RNA an infected cell makes; both forms are necessary for HIV to replicate. The critical nucleotide happens to be in a region of the HIV genome with low mutation rates. That placement makes it a promising target for new therapies, because the virus is less likely to develop resistance.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423143131.htm

3D face photos could be a sleep apnea screening tool

Facial features analyzed from 3D photographs could predict the likelihood of having obstructive sleep apnea, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423143057.htm

A new therapeutic target turns the immune system against lymphoma

Scientists have identified a key mechanism that tumor cells use to take advantage of and avoid detection from the immune system. Targeting this mechanism offers a new therapeutic strategy for cancers like Non-Hodgkin lymphoma.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130457.htm

Good news for the wheat-sensitive among us

New research has revealed key insights about the proteins causing two of the most common types of wheat sensitivity - non-celiac wheat sensitivity and occupational asthma (baker's asthma).

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130447.htm

How hearing loss in old age affects the brain

If your hearing deteriorates in old age, the risk of dementia and cognitive decline increases. So far, it hasn't been clear why. A team of neuroscientists has examined what happens in the brain when hearing gradually deteriorates: key areas of the brain are reorganized, and this affects memory.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130446.htm

Falling visibility shows African cities suffering major air pollution increases

Falling visibility in three major African cities reveals that air pollution has increased significantly over the last 45 years - leaving citizens facing further short-term increases in human-made pollution due to increasing urbanization and economic development, a new study reveals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130444.htm

Dietary counselling introduced in infancy leads to better cardiovascular health in adults

Scientists investigated the long-term effects of dietary counseling on cardiovascular health. The individuals, who had participated in the trial between ages 7 months and 20 years, were invited to a follow-up study at the age of 26. The results show that the intervention group who received dietary counseling had lower serum cholesterol level and better insulin sensitivity than those in the control group.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130422.htm

Protein produced in sepsis lowers blood pressure, treatment identified to reverse effects

Scientists show that when a molecule known as c-Jun N-terminal kinase (JNK) becomes active in sepsis, it increases the production of a protein called B-type natriuretic peptide (BNP) -- the more BNP that is produced in sepsis, the greater the deterioration of cardiovascular function. But perhaps more significantly, in mice, the researchers show that JNK and BNP activity can be halted, reversing cardiovascular damage and reducing the risk of death from sepsis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423093727.htm

After a heart attack, physical activity makes you feel better

Heart attack patients who take part in a lifestyle improvement program feel better -- especially when they do additional physical activity.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424093602.htm

Your football team loses a match: You may suffer a heart attack

Lost football games may trigger heart attacks in male fans, according to research presented today on EAPC Essentials 4 You, a scientific platform of the European Society of Cardiology (ESC). 'Our study shows that poor results from the local professional football team coincided with more heart attacks in male residents,' said study author Dr. Lukasz Kuzma of the Medical University of Bialystok, Poland. 'The findings suggest that the mental and emotional stress of defeat can provoke cardiac events.'

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130419.htm

Sensors woven into a shirt can monitor vital signs

Researchers developed a way to incorporate electronic sensors into stretchy fabrics, allowing them to create shirts or other garments that could monitor vital signs such as temperature, respiration, and heart rate.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130408.htm

A novel method to precisely deliver therapeutics inside the body

A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to researchers. Ultrasound then breaks the capsule, allowing the protein to enter the cell.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130404.htm

High density EEG produces dynamic image of brain signal source

Marking a major milestone on the path to meeting the objectives of the NIH BRAIN initiative, researchers advance high-density electroencephalography (EEG) as the future paradigm for dynamic functional neuroimaging.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423082227.htm

New research highlights blood clot dangers of COVID-19

A special report published today in the journal Radiology outlines prevention, diagnosis and treatment of complications stemming from blood clots in patients with COVID-19. The journal also published two research letters and a case study on this topic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423143100.htm

New dual-action coating keeps bacteria from cross-contaminating fresh produce

Over the course of their journey from the open fields to the produce displays at grocery stores, fresh vegetables and fruits can sometimes become contaminated by microorganisms. These items can then spoil other produce, spreading the contamination further and increasing the number of food items that can cause illnesses.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422214044.htm

Diabetes reversed in mice with genetically edited stem cells derived from patients

Researchers have used induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes, transformed the stem cells into insulin-producing cells, used the CRISPR gene-editing tool to correct a defect that caused the diabetes, and implanted the cells into mice to reverse diabetes in the animals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422214036.htm

New targeted agent produces considerable responses in patients with uterine cancer

The DNA repair-blocking drug adavosertib shrinks tumors in nearly one-third of patients in clinical trial data to be shared at the Society for Gynecologic Oncology (SGO) Annual Meeting on Women's Cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423212610.htm

A cellular mechanism protecting against cancer

Researchers have discovered a natural protective mechanism that leads to the programmed death of potentially diseased cells. It protects from cancer that can develop as a result of irregular distribution of genetic information to daughter cells. The enzyme separase plays a central role in these processes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423143104.htm

The most promising strategies for defeating coronavirus: A review study

Experts from UNC Chapel Hill review possible clinical approaches from antivirals to gene therapy against the virus responsible for COVID-19 and related diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424081706.htm

The best material for homemade face masks may be a combination of two fabrics

Researchers report that a combination of cotton with natural silk or chiffon can effectively filter out aerosol particles -- if the fit is good.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424081648.htm

Simple 'do it yourself' circuit to ventilate two patients at once is technically feasible

A simple 'do it yourself' breathing circuit, using accessories that are readily available in intensive care, can be used to ventilate two critically ill patients at once, should clinicians be faced with equipment shortages, new research suggests.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423212619.htm

Two steps closer to flexible, powerful, fast bioelectronic devices

Researchers have designed biocompatible ion-driven soft transistors that can perform real-time neurologically relevant computation and a mixed-conducting particulate composite that allows creation of electronic components out of a single material. These have promise for bioelectronic devices that are fast, sensitive, biocompatible, soft, and flexible, with long-term stability in physiological environments such as the human body. In particular, they could facilitate diagnosis and monitoring of neurological disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424150734.htm

Nursing homes prepared for pandemics, but COVID-19 reveals gaps

New data suggests that Michigan nursing homes that responded to a survey were far better prepared for the COVID-19 pandemic than they were for the last one. The study includes responses from 130 nursing homes to a survey during the week that the state announced its first documented case of COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424132604.htm

COVID-19: The downside of social distancing

When faced with danger, humans draw closer together. Social distancing thwarts this impulse. Researchers argue that this dilemma poses a greater threat to society than overtly antisocial behavior.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200424132539.htm

Electronic skin fully powered by sweat can monitor health

Electronic skin monitors body's vitals signs while being powered by sweat.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422213609.htm

New systematic review captures what makes a positive post-birth experience for new mothers

A new qualitative systematic review conducted to inform the scope of a new World Health Organization (WHO) post-birth (postnatal) guideline identifies four clear themes for a positive experience in mothers across 15 different countries and cultures.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422151113.htm

Human uterus colonized by clones with cancer-driving mutations that arise early in life

Many cells in the inner lining of the uterus carry 'cancer-driving' mutations that frequently arise early in life, report scientists. The research team conducted whole-genome sequencing of healthy human endometrium, providing a comprehensive overview of the rates and patterns of DNA changes in this tissue.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422132933.htm

COVID-19 Puts the Brakes on a Major HIV Bike Ride—but Not Completely

Meanwhile, two similar fundraising events on the East Coast are still gearing up to go!


from POZ RSS - Categories https://www.cancerhealth.com/article/covid19-puts-brakes-major-hiv-bike-ridebut-completely

COVID-19 could cost the United States billions in medical expenses

A new study shows that hospitalizations, ventilators, and other health resources that patients would require could cost the United States $654 billion if a majority of the population gets infected with the COVID-19 coronavirus.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423160512.htm

Inexpensive, portable detector identifies pathogens in minutes

Researchers have demonstrated an inexpensive yet sensitive smartphone-based testing device for viral and bacterial pathogens that takes about 30 minutes to complete. The roughly $50 smartphone accessory could reduce the pressure on testing laboratories during a pandemic such as COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423154154.htm

Experts issue guide on lung cancer screening, management during COVID-19

A new expert panel consensus statement provides guidance to clinicians managing lung cancer screening programs and patients with lung nodules during the COVID-19 pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423143105.htm

Researchers are making recombinant-protein drugs cheaper

The mammalian cell lines that are engineered to produce high-value recombinant-protein drugs also produce unwanted proteins that push up the overall cost to manufacture these drugs. These same proteins can also lower drug quality. Researchers have now shown that their genome-editing techniques could eliminate up to 70 percent of the contaminating protein by mass in recombinant-protein drugs produced by the workhorses of mammalian cells -- Chinese Hamster Ovary (CHO) cells.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423154209.htm

An obesity protein discovery may lead to better treatments

By determining the structure of a key receptor in obesity, scientists have unlocked an opportunity for the development of new drugs.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423154200.htm

Game theory suggests more efficient cancer therapy

Mathematicians are using game theory to model how this competition could be leveraged, so cancer treatment -- which also takes a toll on the patient's body -- might be administered more sparingly, with maximized effect.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423154152.htm

Novel coronavirus detected, monitored in wastewater

A new approach to monitoring the novel coronavirus (as well as other dangerous pathogens and chemical agents) is being developed and refined. Known as wastewater-based epidemiology (WBE), the method mines sewage samples for vital clues about human health. It can potentially identify levels of coronavirus infection at both a local and global scale.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423144056.htm

Promising MERS coronavirus vaccine trial in humans

Scientists have now conducted a first-in-human trial with a vaccine against MERS (Middle East Respiratory Syndrome). The MVA-MERS-S vaccine was tolerated well and triggered the development of antibodies and T cell immunity.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422132600.htm

DNA may not be life's instruction book -- just a jumbled list of ingredients

The common view of heredity is that all information passed down from one generation to the next is stored in an organism's DNA. But one research suggests this might not be so. In two new papers, he argues DNA is just the ingredient list, not the set of instructions used to build and maintain a living organism. The instructions, he says, are stored in the molecules that regulate a cell's DNA and other functioning systems.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422112303.htm

Key nose cells identified as likely COVID-19 virus entry points

Two specific nose cell types have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells, which could help explain the high rate of transmission. The study with Human Cell Atlas Lung Biological Network found cells in the eye and some other organs also contain the viral-entry proteins.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130420.htm

How to make the healthiest coffee

What's the healthiest way to make a fresh cup of coffee? A new study examining links between coffee brewing methods and risks of heart attacks and death has concluded that filtered brew is safest.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422214101.htm

'Designer virus' is first new oral polio vaccine in 50 years

Virologists report promising Phase 1 clinical results for the first new oral polio vaccine in 50 years, which they have designed to be incapable of evolving the ability to cause disease in humans.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130455.htm

Researchers restore injured man's sense of touch using brain-computer interface technology

Researchers have been able to restore sensation to the hand of a research participant with a severe spinal cord injury using a brain-computer interface (BCI) system. The technology harnesses neural signals that are so minuscule they can't be perceived and enhances them via artificial sensory feedback sent back to the participant, resulting in greatly enriched motor function.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130508.htm

Very low-dose Avastin effective for preventing blindness in preterm infants

Babies born prematurely who require treatment to prevent blindness from retinopathy of prematurity (ROP) could be treated with a dose of Avastin (bevacizumab) that is a fraction of the dose commonly used for ROP currently.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130503.htm

New test for COVID-19 may deliver faster results to more people

Scientists have developed a novel assay capable of detecting the causative viral pathogen of COVID-19 that can be run in decentralized test facilities, according to a new report.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423130412.htm

Coronaviruses and bats have been evolving together for millions of years

Scientists compared the different kinds of coronaviruses living in 36 bat species from the western Indian Ocean and nearby areas of Africa. They found that different groups of bats have their own unique strains of coronavirus, revealing that bats and coronaviruses have been evolving together for millions of years. Developing a better understanding of how coronaviruses evolved can help us create better public health programs for the future.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200423082231.htm

Primary Care Docs Not Keen to Prescribe Opioid Use Disorder Treatment

A national survey found that primary care physicians had little interest in prescribing buprenorphine or naltrexone.


from POZ RSS - Categories https://www.cancerhealth.com/article/primary-care-docs-keen-prescribe-opioid-use-disorder-treatment

Specialized nerve cells increase the appetite for high-fat foods

Fat activates nociceptin neurons in the hypothalamus of mice.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422112241.htm

Spinal cord injury increases risk for mental health disorders

A new study finds adults with traumatic spinal cord injury are at an increased risk of developing mental health disorders and secondary chronic diseases compared to adults without the condition.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422101536.htm

Ef­fects of rapid-act­ing an­ti­de­press­ants con­sol­id­ated in sleep?

Ketamine alleviates depressive symptoms within hours, with the most significant change typically seen a day after its administration. However, the symptoms often reappear within a week. According to researchers, neural connections strengthened by the quick treatment of depression are consolidated in the brain during the deep sleep periods of the following night. To prevent the circle of negative thoughts regaining supremacy, depressed patients also need therapy.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422101534.htm

New heart attack testing protocol expedites treatment in ER

A new protocol using highly sensitive blood tests to determine whether someone is having a heart attack.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422214051.htm

Which foods do you eat together? How you combine them may raise dementia risk

It's no secret that a healthy diet may benefit the brain. However, it may not only be what foods you eat, but what foods you eat together that may be associated with your risk of dementia, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422214038.htm

$90K Settlement in HIV Discrimination Case Against Sheriff’s Office

“This settlement is a lesson to all employers that HIV discrimination in the workplace is completely unlawful and has no place anywhere.”


from POZ RSS - Categories https://www.cancerhealth.com/article/90k-settlement-hiv-discrimination-case-sheriffs-office

Researchers identify cells likely targeted by COVID-19 virus

Researchers have identified specific types of cells that appear to be the targets of the SARS-Cov-2 coronavirus that is causing the Covid-19 pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422132556.htm

Small rises in blood glucose trigger big changes in insulin-producing cells

This study provides a wealth of new data showing how beta cells behave at slightly raised levels of blood glucose -- still within the pre-diabetes range. The work provides major additional evidence of a 'glucose toxicity' effect that helps to drive the development of both type 1 and type 2 diabetes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421134424.htm

Football offensive linemen should start plays upright to avoid hits to the head

Just a simple change to the starting stance of players on the offensive line in American football could significantly reduce hits to the head, a new study now shows.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112543.htm

Helping the heart heal itself

Scientists have discovered a protein that works with others during development to put the brakes on cell division in the heart.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422151316.htm

Researchers uncover mechanisms of protective antibody response during Marburg infection

A detailed study of the monoclonal antibodies from a person who survived a Marburg infection led researchers to identify novel mechanisms that contribute protection against the disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421134400.htm

A breakthrough in estimating the size of a (mostly hidden) network

A newly discovered connection between control theory and network dynamical systems could help estimate the size of a network even when a small portion is accessible. Understanding the spread of coronavirus may be the most alarming recent example of a problem that could benefit from fuller knowledge of network dynamical systems, but scientists and mathematicians have grappled for years with ways to draw accurate inferences about these complex systems from available measurements.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422132835.htm

Scientists shed new light on viral protein shell assembly

New insight on the conditions that control self-assembly in the protective shell of viruses has just been published.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112559.htm

Expansion of world's cities creating 'new ecological niches' for infectious diseases

New research highlights how urban expansion is creating the conditions for infectious diseases to emerge and spread around the world by blurring the classical boundaries between city, suburb, and countryside.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112557.htm

How cancer cells don their invisibility cloaks

Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic results.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112555.htm

New macrolactone database could aid drug discovery, research

Researchers have created a free-to-use database of 14,000 known macrolactones -- large molecules used in drug development -- which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112553.htm

Research reveals a new malaria vaccine candidate

In a study that could lead to a new vaccine against malaria, researchers have found antibodies that trigger a 'kill switch' in malarial cells, causing them to self-destruct.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422132930.htm

Ultrasound-assisted molecule delivery looks to preserve blood for years

Blood can typically be stored for only six weeks after donation, but a potential solution attempts to dry blood by using a sugar-based preservative. New work in ultrasound technology looks to provide a path to inserting these sugars into human red blood cells, allowing the molecule trehalose to enter the cells and prevent their degradation when dried for preservation.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112536.htm

Cost-effective canopy protects health workers from COVID infection during ventilation

Researchers have designed a cost-effective, plastic canopy system that can help to protect healthcare workers who are at risk of airborne coronavirus infection while delivering noninvasive ventilation or oxygen via high flow nasal canula (HFNC). Noninvasive ventilation or HFNC is often used to support breathing following respiratory failure, which is a common symptom of severe coronavirus disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420201511.htm

Low-cost, easy-to-build ventilator performs similarly to high-quality commercial device

A low-cost, easy-to-build non-invasive ventilator aimed at supporting the breathing of patients with respiratory failure performs similarly to conventional commercial devices. Researchers say the prototype ventilator could support treatment of coronavirus and other severe respiratory diseases in low income regions or where ventilator supplies are limited. The research paper provides a free to replicate, open source description for how to build the ventilator.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420201508.htm

New application of machine learning and image analysis to help distinguish a rare subtype of kidney cancer

Despite significant obstacles presented by COVID-19, Regenstrief Institute Affiliated Scientist Jie Zhang, PhD, Regenstrief Institute Research Scientist Kun Huang, PhD, both Indiana University School of Medicine faculty members, and Jun Cheng, PhD of Shenzhen University conducted a study applying machine learning and image analysis to distinguish a rare subtype of kidney cancer (tRCC) while Dr. Cheng was quarantined in Wuhan.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420165712.htm

Segregation and local funding gaps drive disparities in drinking water

The fragmentation of water service in the US among thousands of community systems, most of which are small and rely on local funding, leaves many households vulnerable to water contamination or loss of service as droughts become more frequent, a new analysis finds. Households in low-income or predominantly minority neighborhoods face the highest risks. Making sure their taps don't run dry will require a fundamental re-evaluation of how water systems are managed and funded.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420201515.htm

A new biosensor for the COVID-19 virus

Researchers have developed a novel sensor for detecting the new coronavirus. In future, it could be used to measure the concentration of the virus in the environment -- for example, in places where there are many people or in hospital ventilation systems.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112520.htm

Scientists explore using 'own' immune cells to target infectious diseases including COVID-19

The engineering of specific virus-targeting receptors onto a patient's own immune cells is now being explored by scientists as a potential therapy for controlling infectious diseases, including the COVID-19-causing virus, SARS-CoV-2.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112518.htm

Autoimmunity plays a role in Parkinson's disease, study suggests

A new study co-led by scientists at the La Jolla Institute for Immunology (LJI) adds increasing evidence that Parkinson's disease is partly an autoimmune disease. In fact, the researchers report that signs of autoimmunity can appear in Parkinson's disease patients years before their official diagnosis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420084255.htm

Link between obesity and sleep loss

Can staying up late make you fat? Researchers found the opposite to be true when they studied sleep in worms: It's not the sleep loss that leads to obesity, but rather that excess weight can cause poor sleep.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422091205.htm

Researchers develop new microneedle array combination vaccine delivery system

In parallel to their current work on a potential coronavirus vaccine, researchers have developed a new vaccine delivery system for vaccines using live or attenuated viral vectors: a finger-tip sized patch that contains 400 tiny needles, each just half of one millimeter.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422091203.htm

Novel class of specific RNAs may explain increased depression susceptibility in females

Researchers have found that a novel class of genes known as long non-coding RNAs (lncRNAs) expressed in the brain may play a pivotal role in regulating mood and driving sex-specific susceptibility versus resilience to depression.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200422091157.htm

$155M in Federal COVID-19 Relief Funds Goes to HIV Programs

Here’s how HIV funding from the CARES Act gets divided


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Human pregnancy is weird -- new research adds to the mystery

Scientists set out to investigate the evolution of a gene that helps women stay pregnant: the progesterone receptor gene. The results come from an analysis of the DNA of 115 mammalian species.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112542.htm

Pulse oximetry monitoring overused in infants with bronchiolitis

Monitoring blood oxygen levels with continuous pulse oximetry is being overused in infants with bronchiolitis who do not require supplemental oxygen, according to a new study. The researchers found the use of continuous pulse oximetry occurred frequently and varied widely among hospitals in their sample, despite national recommendations advising against the practice.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112540.htm

CRISPR helps identify potential Alzheimer's-related protein

Experts have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the 'molecular scissors' of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease. Researchers tested a total of 19,150 individual genes for their effect on amyloid beta levels and ruled out all but one: calcium and integrin-binding protein 1 (CIB1).

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112529.htm

Glaucoma could be successfully treated with gene therapy

A new study has shown a common eye condition, glaucoma, could be successfully treated with a single injection using gene therapy, which would improve treatment options, effectiveness and quality of life for many patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112608.htm

Milestone for the early detection of sepsis

Researchers are developing a ground-breaking method that uses biomarkers to detect sepsis 2 to 3 days before the first clinical symptoms appear. This can significantly increase the chances of survival in cases of blood poisoning by bacteria or fungi.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112512.htm

Heavy cost of excessive drinking on people's decision making

A new study highlights how hangover inhibits individuals' 'core executive functions' with knock-on impacts for those currently working from home.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421112508.htm

Got seasonal allergies? Beetles could help

Allergies caused by the common ragweed, Ambrosia artemisiifolia, impact millions, and in Europe alone, around 13.5 million people suffer with symptoms, resulting in 7.4 billion Euros worth of health costs per year, according to the research. The study suggests the leaf beetle, Ophraella communa, could reduce the number of people affected by the pollen and the associated economic impacts, since the beetle -- itself a recent arrival in Europe -- loves to munch on the invasive plant.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421134422.htm

Antibodies could provide new treatment for OCD

Mental health conditions such as obsessive compulsive disorder could be treated in a new way using drugs that target the immune system, research suggests.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421094257.htm

AI to make dentists' work easier

Researchers have developed a new automatized way to localize mandibular canals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421094254.htm

Use of Mental Health Meds Has Increased During COVID-19

Experts found that Americans filled more prescriptions for antidepressants, anti-anxiety and anti-insomnia drugs.


from POZ RSS - Categories https://www.cancerhealth.com/article/use-mental-health-meds-increased-covid19

Continued CO2 emissions will impair cognition

New research finds that an anticipated rise in carbon dioxide concentrations in our indoor living and working spaces by the year 2100 could lead to impaired human cognition.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421090556.htm

Age matters: Paternal age and the risk of neurodevelopmental disorders in children

It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200421090538.htm

HIV Nonprofit Housing Works Opens COVID-19 Homeless Shelters

Both shelters are located in New York City hotels.


from POZ RSS - Categories https://www.cancerhealth.com/article/hiv-nonprofit-housing-works-opens-covid19-homeless-shelters

Some Methadone Clinics Aren’t Following Social Distancing Guidelines

Even after federal regulators relaxed rules requiring daily clinic visits, these bad actors are still bringing patients in for monitoring.


from POZ RSS - Categories https://www.cancerhealth.com/article/methadone-clinics-following-social-distancing-guidelines

Researchers repurpose classic chemotherapy drug to overcome cancer therapy resistance

Drug resistance is a major obstacle in cancer treatment -- leading to relapse for many patients. In a new study, researchers report on a promising new strategy to overcome drug resistance in leukemia, using targeted doses of the widely-used chemotherapy drug doxorubicin.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420165730.htm

Early exposure to cannabis boosts young brains' sensitivity to cocaine, rodent study finds

Cannabis use makes young brains more sensitive to the first exposure to cocaine, according to a new study on rodents. By monitoring the brains of both adolescent and adult rats after giving them synthetic psychoactive cannabinoids followed by cocaine, the research team identified key molecular and epigenetic changes that occurred in the brains of adolescents -- but not adults.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420165718.htm

Finding leukemia's weakness using genome-wide CRISPR technology

Researchers have used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420125543.htm

Unprecedented single-cell studies in virtual embryo

Researchers have created the first complete description of early embryo development, accounting for every single cell in the embryo. This 'virtual embryo' will help to answer how the different cell types in an organism can originate from a single egg cell.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420125536.htm

Turning on the 'off switch' in cancer cells

A team of scientists has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer. The discovery marks a critical step toward developing a potential new class of anti-cancer drugs that enhance the activity of a prevalent family of tumor suppressor proteins, the authors say.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420125521.htm

Aquaculture at the crossroads of global warming and antimicrobial resistance

Antimicrobial resistance is responsible for some 700,000 deaths each year worldwide. In relation to this phenomenon, researchers have raised the alarm regarding the development of antimicrobial-resistant bacteria in aquaculture, which is affecting fish production and human health worldwide. Their study established for the first time a link between global warming and an increased risk of antimicrobial resistance, and warned against inappropriate use of antibiotics.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420125439.htm

Male-female cardiac repair differences in heart failure survival after heart attack

A new study investigated the molecular and cellular processes underlying cardiac repair in male and female mice after a severe heart attack. The researchers discovered that heart repair happened faster in the female mice than the males after heart attack, and that improved survival and delayed cardiac failure.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420104858.htm

Unprecedented 3D images of live cells plus details of molecules inside

The insides of living cells can be seen in their natural state in greater detail than ever before using a new technique. This advance should help reveal the complex and fragile biological interactions of medical mysteries, like how stem cells develop or how to deliver drugs more effectively.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420105051.htm

New decision model shapes strategies for dealing with public health emergencies

The efficient allocation of medical resources can be modelled mathematically. The study, which started a few years before coronavirus appeared, offers timely insights for governments and organizations who are faced with an unprecedented healthcare crisis. Specifically, it presents a comprehensive decision model for optimizing the use of alternative tests and treatments on specific population groups, and suggests that even less-than-perfect tests can help improve effective spending limited healthcare resources.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420104850.htm

Type 2 diabetes: Too much glucagon?

Patients with type 2 diabetes secrete not only too little insulin but also too much glucagon, which contributes to poor blood glucose control.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420110018.htm

Maternal hypertensive disorders may lead to mental health disorders in children

Hypertensive pregnancy disorders, especially preeclampsia -- may increase the risk of psychological development disorders and behavioral and emotional disorders in children. This is the first study to show that preeclampsia predicts increased offspring risk of any childhood mental disorder, regardless of mental disorders in the parents and other conditions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200420084242.htm

See Scraps From the AIDS Memorial Quilt Made Into Coronavirus Masks

Volunteers sew the masks for frontline workers serving homeless and underserved communities.


from POZ RSS - Categories https://www.cancerhealth.com/article/see-scraps-aids-memorial-quilt-made-coronavirus-masks

Novel technology aims to improve treatment of neurological diseases

Researchers are developing new 'gene promoters' - which act like switches to turn genes on - for use with gene therapy, the delivery of new genes to replace ones that are faulty. The new promoters work especially well for brain and other neurological disorders and provide longer-lasting functionality compared to other promoters.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417212938.htm

Researchers achieve remote control of hormone release

Using magnetic nanoparticles, scientists stimulate the adrenal gland in rodents to control release of hormones linked to stress.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417212933.htm

A key brain region for controlling binge drinking has been found

A team of researchers has found that turning off a stress signaling system in a single specific brain area can reduce harmful binge drinking. This finding brings researchers one step closer to understanding which signals in the brain drive individuals to consume alcohol excessively and put them at risk for developing an alcohol use disorder.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417212907.htm

Relying on 'local food' is a distant dream for most of the world

A recent study shows that less than one-third of the world's population could currently meet their demand for food produced in their local vicinity.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417114517.htm

Simulations show how to make gene therapy more effective

Diseases with a genetic cause could be treated by supplying a correct version of the faulty gene. However, in practice, delivering new genetic material to human cells is difficult. A promising method for the delivery of such genes involves the use of DNA/lipid complexes (lipoplexes). Scientists have now used advanced simulations to investigate how these lipoplexes deliver DNA fragments into cells. The results can be used to improve their efficiency.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417114509.htm

Stem cells in human embryos commit to specialization surprisingly early

The point when human embryonic stem cells irreversibly commit to becoming specialized has been identified by researchers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417114447.htm

Cancer drug resistance study raises immune red flags

Once a cancer patient's tumors develop resistance to chemotherapy, the prognosis can be poor. However, inhibiting a key gene involved in multidrug resistance, MDR1, has not improved outcomes. A new study offers a reason, revealing unintended downstream effects on immune system cells.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417114440.htm

Under pressure: New bioinspired material can 'shapeshift' to external forces

Inspired by how human bone and colorful coral reefs adjust mineral deposits in response to their surrounding environments, researchers have created a self-adapting material that can change its stiffness in response to the applied force. This advancement can someday open the doors for materials that can self-reinforce to prepare for increased force or stop further damage.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417114438.htm

Nasal smear as an allergy screening test

In the world of allergy diagnostics, the familiar blood samples and unpleasant skin prick procedures for testing allergen tolerance may soon be a thing of the past. A team of researchers has demonstrated that sufficient quantities of allergy antibodies for a diagnosis can be effectively measured in nasal secretions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417103819.htm

New chemical tools can control the concentration of lipids in living cells

So far, it has been difficult to analyze the functions of lipid molecules in living cells. Researchers have now developed chemical tools that can be activated by light and used to influence lipid concentration in living cells. This approach could enable medical doctors to work with biochemists to identify what molecules within a cell do.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417103816.htm

Lighting the way to safer heart procedures

In the first study of its kind, researchers provide evidence that an alternative imaging technique could someday replace current methods that require potentially harmful radiation.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417081631.htm

Neural circuits mapped: Now we understand vision better

Researchers have discovered the function of a special group of nerve cells which are found in the eye and which sense visual movement. The findings give us a completely new understanding of how conscious sensory impressions occur in the brain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416135921.htm

New universal Ebola vaccine may fight all four virus species that infect humans

Infectious disease scientists report early development of a potential universal vaccine for Ebola viruses that preclinical tests show might neutralize all four species of these deadly viruses infecting people in recent outbreaks, mainly in Africa. Although still in early preclinical testing, researchers report that their data indicate that the prospective vaccine has potential to be a stand-alone protection from Ebola.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416135853.htm

Review assesses stem cell therapy potential for treating preeclampsia

A review of using stem cells to treat preeclampsia, a dangerous condition in pregnancy, indicates that mesenchymal stem/stromal cells (MSCs), or their secreted vesicles, have the potential to be used as therapies that could progress to clinical trials.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416091944.htm

Mysterious tuft cells found to play role in pancreatitis

Scientists have uncovered the formation of tuft cells during pancreatitis and the surprising role of these cells in immunity, using mouse models of pancreatitis. The findings could lead to the development of new biomarkers to test for pancreatitis and pancreatic cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417212928.htm

Micro-device to detect bacteria, viruses

Scientists designed a next-generation miniature lab device that uses magnetic nano-beads to isolate minute bacterial particles that cause diseases. This new technology improves how clinicians isolate drug-resistant strains of bacterial infections and difficult-to-detect micro-particles such as those making up Ebola and coronaviruses.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417212926.htm

National Transgender HIV Testing Day 2020

About 1.4 million adults in the United States identify as transgender. Many are at high risk of HIV.


from POZ RSS - Categories https://www.cancerhealth.com/article/national-transgender-hiv-testing-day-2020

Genomics used to estimate Samoan population dynamics over 3,000 years

A new study estimating the size of the Samoan population using contemporary genomic data found that the founding population remained low for the first 1,500 years of human settlement, contributing to understanding the evolutionary context of the recent rise in obesity and related diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200417103148.htm

How exercise supports your mental fitness: Current recommendations

Sporting activities can bring about a long-term improvement in cognitive performance across all age groups. However, the effects differ between men and women, and not all sports provide the same impact. Researchers have provided recommendations based on a comprehensive analysis of previous studies.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416135913.htm

New clues to predict the risks astronauts will face from space radiation on long missions

Researchers used a novel approach to test assumptions in a model used by NASA to predict health risks for astronauts.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416135857.htm

Scents regulate fat storage without affecting eating behavior

Researchers discovered that, in the lab worm C. elegans, certain scents dynamically regulate fat mobilization by interacting with specific olfactory neurons through specific receptors.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416151756.htm

Study finds evidence for existence of elusive 'metabolon'

For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or 'metabolons,' in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers, for the first time, have directly observed functional metabolons involved in generating purines, the most abundant cellular metabolites. The findings could lead to the development of novel therapeutic strategies that disrupt the progression of cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416151734.htm

Researchers get important glimpse into microbiome development in early life

A team of researchers has characterized how the gut microbiome develops in the first hours of infancy, providing a critical baseline for how changes in this environment can impact health and disease later in life.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416151714.htm

Whole genome sequencing reveals genetic structural secrets of schizophrenia

Scientists have conducted the largest-ever whole genome sequencing study of schizophrenia to provide a more complete picture of the role the human genome plays in this disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416151704.htm

A non-invasive way of monitoring diabetes

Saliva could be used instead of blood to monitor diabetes in a new method.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416135954.htm

Treatment for spasticity in mice, following spinal cord injuries discovered

In experiments with mice, researchers have studied neuronal mechanisms and found a way to by and large prevent spasticity from developing after spinal cord injuries. A new study shows that the researchers have done this by using already approved medicine for high blood pressure.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416114543.htm

Psychedelic compound from magic mushrooms produced in yeast

Scientists prove that psilocybin, a potential drug for treating depression and other psychological conditions can be produced in yeast.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416114535.htm

Physicians Launch HIV and COVID-19 Registry

New database will collect information about cases of the novel coronavirus among people living with HIV.


from POZ RSS - Categories https://www.cancerhealth.com/article/physicians-launch-hiv-covid19-registry

Proteins may halt the severe cytokine storms seen in COVID-19 patients

A team of researchers has developed specialized antibody-like receptor proteins that they believe could soak up the excess cytokines produced during a cytokine storm. This excessive immune response, sometimes seen in Covid-19 patients, can be fatal.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416135950.htm

Genetics linked to childhood emotional, social and psychiatric problems

Emotional, social and psychiatric problems in children and adolescents have been linked to higher levels of genetic vulnerability for adult depression.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416094212.htm

R.I.P. Garry Bowie; the HIV Activist and Nonprofit Leader Died of COVID-19

Bowie oversaw the West Hollywood AIDS group Being Alive. Explore his meaningful life in these social media posts.


from POZ RSS - Categories https://www.cancerhealth.com/article/rip-garry-bowie-hiv-activist-nonprofit-leader-died-covid19

Lung-heart super sensor on a chip tinier than a ladybug

This Lilliputian chip's detection bandwidth is enormous -- from sweeping body motions to faint sounds of the heartbeat, pulse waves traversing body tissues, respiration rate, and lung sounds.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416091949.htm

Influenza: researchers show that new treatment reduces spread of virus

Researchers have shown that a new antiviral drug for influenza can treat the infection at the same time as reducing the risk of transmission to others, offering powerful potential to change the way we manage influenza outbreaks -- particularly in vulnerable groups.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200416091947.htm

Bile metabolite of gut microbes boosts immune cells

A new study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415152915.htm

Aspirin linked to reduction in risk of several cancers of the digestive tract

The largest and most comprehensive analysis to date of the link between aspirin and cancers of the digestive tract has shown that it is associated not only with a significant reduction in the risk of developing bowel cancer but also of several other cancers that almost invariably fatal, such as pancreatic and liver cancers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415200520.htm

Obesity is a critical risk factor for type 2 diabetes, regardless of genetics

Obesity increases the risk of developing type 2 diabetes by at least 6 times, regardless of genetic predisposition to the disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415185837.htm

Low-cost imaging system poised to provide automatic mosquito tracking

Mosquito-transmitted diseases such as malaria, dengue and yellow fever are responsible for hundreds of thousands of deaths every year. A new low-cost imaging system could make it easier to track mosquito species that carry disease, enabling a more timely and targeted response.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415171435.htm

Prescribing an overdose: A chapter in the opioid epidemic

Research indicates that widespread opioid overprescribing contributed to the opioid epidemic. New research shows that this dangerous trend has apparently been coupled with another: inappropriate use of high-potency opioids.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133516.htm

Antiviral drug baloxavir reduces transmission of flu virus among ferrets

Baloxavir treatment reduced transmission of the flu virus from infected ferrets to healthy ferrets, suggesting that the antiviral drug could contribute to the early control of influenza outbreaks by limiting community-based viral spread.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415152917.htm

Biomechanics of skin can perform useful tactile computations

As our body's largest and most prominent organ, the skin also provides one of our most fundamental connections to the world around us. From the moment we're born, it is intimately involved in every physical interaction we have.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415152913.htm

Researchers use snake venom to solve structure of muscle protein

Researchers have uncovered the detailed shape of a key protein involved in muscle contraction.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133644.htm

A gut-to-brain circuit drives sugar preference and may explain sugar cravings

The sensation of sweetness starts on the tongue, but sugar molecules also trip sensors in the gut that directly signal the brain. This could explain why artificial sweeteners fail to satisfy the insatiable craving for sugar.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133627.htm

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision, sidestepping the need for stem cells. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals' eyes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133529.htm

Childhood exposure to parental smoking linked to poorer cognitive function in midlife

A new study shows that exposure to parental smoking in childhood and adolescence is associated with poorer learning ability and memory in midlife.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133447.htm

Crohn's disease: Preserving inflammation-free phases

Crohn's disease is a chronic inflammatory disorder of the intestine that, in most cases, relapses episodically. As of now, there is no cure for this disease. A research group has discovered a marker at a microscopic level, which can be used to identify patients that show a high probability of suffering from an inflammation recurrence in the immediate future. With this insight, therapeutic counter-measures may be employed at an earlier stage.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133435.htm

New textile could keep you cool in the heat, warm in the cold

Imagine a single garment that could adapt to changing weather conditions, keeping its wearer cool in the heat of midday but warm when an evening storm blows in. In addition to wearing it outdoors, such clothing could also be worn indoors, drastically reducing the need for air conditioning or heat. Now, researchers have made a strong, comfortable fabric that heats and cools skin, with no energy input.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133440.htm

Alzheimer's patients may need dosing changes in medicines prescribed for other conditions

Patients with Alzheimer's disease (AD) are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia. That practice might need to be reexamined in the wake of new mouse studies. The findings suggest that AD could alter absorption of medications from the digestive tract, so dosages might need to be adjusted for these patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133438.htm

How probiotic Bifidobacteria could help celiac disease patients

Gluten is enemy No. 1 for those with celiac disease, and it's hard to avoid. Episodes of this chronic autoimmune illness can be triggered by ingesting gluten, a key protein in wheat and some other grains. Researchers have been exploring how gut bacteria, especially Bifidobacteria, could be used as a treatment. Now, scientists report how specific types of Bifidobacteria work.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133426.htm

Watch Magic Johnson Talk Coronavirus, HIV and Racial Disparities

The sports legend appeared on a CNN town hall. He’s got opinions—and advice.


from POZ RSS - Categories https://www.cancerhealth.com/article/watch-magic-johnson-talk-coronavirus-hiv-racial-disparities

COPD as a lung stem cell disease

Two stem cell researchers have found an abundance of abnormal stem cells in the lungs of patients who suffer from Chronic Obstructive Pulmonary Disease (COPD), a leading cause of death worldwide. The team, who used single cell cloning of lung stem cells to make their discovery, is now targeting the cells for new therapeutics.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415133646.htm

Improving the treatment of periodontitis

For the first time, researchers have shown that a unicellular parasite commonly found in the mouth plays a role in both severe tissue inflammation and tissue destruction.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415132825.htm

Soot may only be half the problem when it comes to cookstoves

Researchers spent two weeks in India cooking with local residents. They found that soot wasn't the only worrisome byproduct of traditional cookstoves; organic carbons are causing problems, too.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415110459.htm

A more plant-based diet without stomach troubles: Getting rid of FODMAPs with enzymes

A plant-based diet is a good choice for both climate and health. However, many plant-based products, especially legumes, contain FODMAP compounds that are poorly digestible and cause unpleasant intestinal symptoms. A study has succeeded in breaking down FODMAPs with enzymes and producing new, stomach-friendly plant-based food products.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415110457.htm

Breastfeeding may lead to fewer human viruses in infants

Even small amounts of breastmilk strongly influences the accumulation of viral populations in the infant gut and provides a protective effect against potentially pathogenic viruses, according to researchers who examined hundreds of babies.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415110452.htm

Mouse study shows 'chaperone protein' protects against autoimmune diseases

Like a parent of teenagers at a party, Mother Nature depends on chaperones to keep one of her charges, the immune system, in line so that it doesn't mistakenly attack normal cells, tissues and organs in our bodies.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415110450.htm

Breathing heavy wildfire smoke may increase risk of out-of-hospital cardiac arrest

Heavy wildfire smoke may raise the risk of out-of-hospital cardiac arrest. To reduce exposure to wildfire smoke, researchers advise people to stay indoors with doors and windows closed, to use high-efficiency air filters in air conditioning systems, avoid exertion, and consider seeking shelter elsewhere if the home does not have an air conditioner and it is too warm to stay inside.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415084314.htm

Breeding a hardier, more nutritious wheat

High-fructan wheat provides benefits for growers and consumers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200415084310.htm

Being right-brained or left-brained comes down to molecular switches

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are 'right-brained' while others are 'left-brained.' The answer lies in how certain genes on each side of the brain are switched 'on' and 'off' through a process called epigenetic regulation. The findings may explain why Parkinson's disease and other neurological disorders frequently affect one side of the body first, a revelation that has far-reaching implications for development of potential future treatments.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414173725.htm

Transposable elements play an important role in genetic expression and evolution

A new study shows that transposable elements play an important role in regulating genetic expression with implications to advance the understanding of genetic evolution.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414173718.htm

Big variability in blood pressure readings between anatomical sites

Blood pressure readings taken from neuroscience intensive care unit (NSICU) patients had marked differences between opposite sides of the body and different anatomical sites in each individual.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414173708.htm

Ultraviolet LEDs prove effective in eliminating coronavirus from surfaces and, potentially, air and water

Researchers are developing ultraviolet LEDs that have the ability to decontaminate surfaces -- and potentially air and water -- that have come in contact with the SARS-CoV-2 virus.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414173251.htm

Keratin scaffolds could advance regenerative medicine and tissue engineering for humans

Researchers have developed a simple method for preparing 3D keratin scaffold models which can be used to study the regeneration of tissue.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414125800.htm

Scientists provide new insight on how bacteria share drug resistance genes

Researchers have been able to identify and track the exchange of genes among bacteria that allow them to become resistant to drugs, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414122821.htm

A Call for Big Changes to Ease Access to Opioid Use Disorder Treatment

The coronavirus pandemic has upended the usual systems governing the dispensation of medication-assisted treatment.


from POZ RSS - Categories https://www.cancerhealth.com/article/call-big-changes-ease-access-opioid-use-disorder-treatment

Gilead’s $20M COVID-19 Fund Will Help HIV Nonprofits

Groups already receiving grants from the pharma giant can apply for new funds during the coronavirus crisis.


from POZ RSS - Categories https://www.cancerhealth.com/article/gileads-20m-covid19-fund-will-help-hiv-nonprofits

Experimental drug offers hope for preventing cancer relapse

A drug that is well-tolerated in patients and prevents cancer coming back in mice has been identified.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414122824.htm

How cells recognize uninvited guests

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team has now discovered how this sensor plays an important role in defending human cells against intruders. The enzymes RNaseT2 and RNase2 cut ribonucleic acids (RNAs) of bacteria into small fragments that are as characteristic as a thumbprint. Only then can TLR8 recognize the dangerous pathogens and initiate countermeasures.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414122826.htm

Mouse study shows how advancing glioma cells scramble brain function, blood flow

The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered a side effect of the tumor. But now a joint team of Columbia engineers and cancer researchers studying brain tumors has found evidence that the seizures caused by an enlarging tumor could spur its deadly progression.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414122752.htm

Experience matters for immune cells

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer, and what goes wrong in immune diseases. Researchers found that T cells responded very differently to immune signals the more 'training' they had been exposed to. This could help guide research into finding drug targets for immune diseases such as asthma and rheumatoid arthritis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414122750.htm

Geneticists zeroing in on genes affecting life span

Researchers quantified variation in life span in the fruit fly genome, providing valuable insights for understanding human disease and aging.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414122748.htm

Spider venom key to pain relief without side-effects

Molecules in tarantula venom could be used as an alternative to opioid pain killers for people seeking chronic pain relief.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/04/200414105558.htm