Microbes in the gut could be protective against hazardous radiation exposure

Scientists showed that mice exposed to potentially lethal levels of total body radiation were protected from radiation damage if they had specific types of bacteria in their gut. They demonstrated that the bacteria mitigated radiation exposure and enhanced the recovery of blood cell production as well as repair of the gastrointestinal tract.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111741.htm

Mothers pass on allergies to offspring

Maternal antibodies primed to react to specific allergens can cross the placenta, passing on transiently allergic reactions to offspring, according to new preclinical research. The finding hints at why infants exhibit allergies so early in life and suggests possible targets for intervention.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111832.htm

A new way to create a spectrum of natural-looking hair colors

Northwestern University researchers have developed a new way to create a spectrum of natural-looking hair colors, ranging from blond to black, by using enzymes to catalyze synthetic melanin.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111828.htm

Compression garments reduce strength loss after training

Regular training enhances your strength, but recovery is equally important. Elastic bandages and compression garments are widely used in sports to facilitate recovery and prevent injuries. Now, a research team has determined that compression garments also reduce strength loss after strenuous exercise.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111821.htm

SARS-CoV-2 spike proteins disrupt the blood-brain barrier, new research shows

New research shows that the spike proteins that extrude from SARS-CoV-2 promote inflammatory responses on the endothelial cells that form the blood-brain barrier. The study shows that SARS-CoV-2 spike proteins can cause this barrier to become 'leaky,' potentially disrupting the delicate neural networks within the brain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029141941.htm

Malaria parasites adapt to survive the dry season

The main parasite that causes malaria can alter its gene expression to survive undetected in the human blood stream, new research has shown.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111811.htm

Beetroot peptide as potential drug candidate for treating diseases

Medical researchers isolated a peptide (small protein molecule) from beetroot. The peptide is able to inhibit a particular enzyme that is responsible for the breakdown of messenger molecules in the body. Due to its particularly stable molecular structure and pharmacological properties, the beetroot peptide may be a good candidate for development of a drug to treat certain inflammatory diseases, such as e.g. neurodegenerative and autoimmune diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111809.htm

Difficult to build a family after exposure to chemical weapons

People who have been exposed to chemical warfare agents (CWAs) feel uncertain, decades after the exposure, about their survival and ability to build a family, a new study shows. Women are more severely affected than men.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111807.htm

Parasitology: Bringing the locals onboard

A new study examines local perceptions of Chagas disease in a region where the infectious agent is endemic. The results underline the need to take social and cultural factors into account in campaigns designed to curb infectious diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201030111803.htm

Face mask aims to deactivate virus to protect others

Researchers have developed a face mask with an embedded antiviral layer that sanitizes the wearer's respiratory droplets to make them less infectious to others.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029142017.htm

Is the COVID-19 pandemic affecting dengue virus case numbers?

The ongoing COVID-19 pandemic has resulted in dramatic changes to human mobility, which has the potential to change the transmission dynamics of other infectious diseases. Now, researchers have found that social distancing has led to a significant increase in dengue infections in Thailand but no change in dengue in Singapore or Malaysia.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029142007.htm

Early results from DETECT study suggest fitness trackers can predict COVID-19 infections

Examining data from the first six weeks of their landmark DETECT study, scientists see encouraging signs that wearable fitness devices can improve public health efforts to control COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029141956.htm

High rate of symptomless COVID-19 infection among grocery store workers

Grocery store employees are likely to be at heightened risk of COVID-19 infection, with those in customer-facing roles 5 times as likely to test positive as their colleagues in other positions, a new study suggests.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029191116.htm

Myocarditis linked to COVID-19 not as common as believed, study shows

A new study suggests myocarditis caused by COVID-19 may be a relatively rare occurrence.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029171653.htm

Models show how COVID-19 cuts a neighborhood path

Researchers have created a new model of how the coronavirus can spread through a community. The model factors in network exposure -- whom one interacts with -- and demographics to simulate at a more detailed level both where and how quickly the coronavirus could spread through Seattle and 18 other major cities.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029171644.htm

Olivia Newton-John’s Breast Cancer Update: “I Feel Wonderful” [VIDEO]

Her new foundation advocates for kinder therapies to fight the disease.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/olivia-newtonjohns-breast-cancer-update-feel-wonderful-video

Comparing sensitivity of all genes to chemical exposure

An environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029171649.htm

World's first agreed guidance for people with diabetes to exercise safely

An academic has helped draw up a landmark agreement amongst international experts, setting out the world's first standard guidance on how people with diabetes can use modern glucose monitoring devices to help them exercise safely. The guidance will be a crucial resource for healthcare professionals around the world, so they can help people with type 1 diabetes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029171642.htm

Muscle pain and energy-rich blood: Cholesterol medicine affects the organs differently

Contrary to expectation, treatment with statins has a different effect on blood cells than on muscle cells, a new study reveals. Today, statins are mainly used in the treatment of elevated cholesterol, but the new results may help design drugs for a number of conditions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029141943.htm

Genomic study reveals role for hypothalamus in inflammatory bowel disease

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029115834.htm

Priming the immune system to attack cancer

New research showed how immune 'training' transforms innate immune cells to target tumors. The findings could inform new approaches to cancer immunotherapy or even strategies for preventing tumor growth.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029115759.htm

Stronger treatments could cure Chagas disease

Researchers have found that a more intensive, less frequent drug regimen with currently available therapeutics could cure the infection that causes Chagas disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029171651.htm

Study identifies pitfall for correcting mutations in human embryos with CRISPR

The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at earliest stage of human development.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029142001.htm

Cancer-fighting gene restrains 'jumping genes'

About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or 'jumping genes,' from hopping around the human genome. In cells with missing or mutated p53, the team found, retrotransposons move and multiply more than usual. The finding could lead to new ways of detecting or treating cancers with p53 mutations.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029105016.htm

How to Vote Safely During the COVID-19 Pandemic

With appropriate precautions, voting in person carries little risk.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/vote-safely-covid19-pandemic

Nucleus accumbens recruited by cocaine, sugar are different

In a study using genetically modified mice, researchers found that the nucleus accumbens recruited by cocaine use are largely distinct from nucleus accumbens recruited by sucrose, or table sugar. Because they are separate, this poses the possibility that drug use can be addressed without affecting biologically adaptive seeking of reward.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029104957.htm

Black soldier fly larvae as protein alternative for hungry humans

Black soldier fly larvae contains more zinc and iron than lean meat and its calcium content is higher than milk. Less than half a hectare of black soldier fly larvae can produce more protein than cattle grazing on around 1200 hectares, or 52 hectares of soybeans. New research has identified the barriers for introducing fly protein into Western human diets as a sustainable, healthy alternative to both meat and plant proteins.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029104951.htm

A groundbreaking genetic screening tool for human organoids

Researchers have developed CRISPR-LICHT, a revolutionary technology that allows genetic screens in human tissues such as brain organoids. By applying the novel technology to brain organoids, the ER-stress pathway was identified to play a major role in regulating the size of the human brain.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029142004.htm

PFAS: These 'forever chemicals' are highly toxic, under-studied, and largely unregulated

Per-/poly-fluroalkyl substances, or PFAS, are everywhere. They are used in firefighting foam, car wax, and even fast-food wrappers. They're one of the most toxic substances ever identified -- harmful at concentrations in the parts per trillion -- yet very little is known about them.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029122943.htm

Brainstem neurons control both behavior and misbehavior

A recent study reveals how gene control mechanisms define the identity of developing neurons in the brainstem. The researchers also showed that a failure in differentiation of the brainstem neurons leads to behavioral abnormalities, including hyperactivity and attention deficit.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029105005.htm

New estimates of breast cancer risks associated with HRT

A new study provides new estimates of the increased risks of breast cancer associated with use of different hormone replacement therapy (HRT) preparations.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028195605.htm

Liquid nanofoam: A game changer for future football helmets

A liquid nanofoam liner undergoing testing could prolong the safe use of football helmets, says a researcher.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028171433.htm

Molecular compass for cell orientation

Plants have veins that transport nutrients through their body. These veins are highly organized. The hormone auxin travels directionally from cell-to-cell and provides cells with positional information, coordinating them during vein formation and regeneration. Scientists now discovered how cells translate auxin signals into forming a complex system of veins. This phenomenon also applies to wound healing and might lead to more mechanically resistant plants and further agricultural implications.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029141949.htm

Positive student-teacher relationships benefit students' long-term health, study finds

Teens who have good, supportive relationships with their teachers enjoy better health as adults, according to new research. Perhaps surprisingly, although friendships are important to adolescents, the study did not find the same link between good peer relationships and students' health in adulthood.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029105030.htm

High-sugar diet can damage the gut, intensifying risk for colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029142042.htm

Denisovan DNA in the genome of early East Asians

Researchers analyzed the genome of the oldest human fossil found in Mongolia to date and show that the 34,000-year-old woman inherited around 25 percent of her DNA from western Eurasians, demonstrating that people moved across the Eurasian continent shortly after it had first been settled by the ancestors of present-day populations. This individual and a 40,000-year-old individual from China also carried DNA from Denisovans, an extinct form of hominins that inhabited Asia before modern humans arrived.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029141740.htm

Positive outlook predicts less memory decline

The happier we feel, the less likely we are to experience memory decline.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029135501.htm

Learning the language of sugars

We're told not to eat too much sugar, but in reality, all of our cells are covered in sugar molecules called glycans. Glycans regulate many important processes including infection by bacteria and viruses, but little is known about them because their structures are highly complex. A team has now created a new suite of deep learning and bioinformatics tools that enable the comprehensive study of glycan sequences, providing insights into their functions and improving our understanding of infectious diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028134036.htm

Social isolation puts women at higher risk of hypertension

Researchers are discovering that social isolation affects the health of men and women in different ways -- including placing women at higher risk of high blood pressure.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028124537.htm

Younger knee replacement patients more likely to require reoperation

Knee replacement surgery, also known as total knee arthroplasty (TKA), is increasing among patients 65 and younger. One study projects a potential 183% increase in the number of TKA and revision TKA surgeries by the year 2030 in that age group, raising concerns about poorer clinical outcomes, lower patient satisfaction and diminished joint survival compared to an older patient population.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028124530.htm

Mechanics of mucus in cystic fibrosis patients

New research examines the properties of the mucus of cystic fibrosis (CF) patients and the role it plays in a pathogens' ability to survive. The new information could have important implications for CF treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028124524.htm

How the immune system deals with the gut's plethora of microbes

New research suggests that our immune system may play an active role in shaping the digestive-tract flora, which is tightly linked to health and disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201029115809.htm

Small brain device proves big game changer for severely paralysed patients

A tiny device the size of a small paperclip has been shown to help patients with upper limb paralysis to text, email and even shop online in the first human trial.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028101844.htm

Postpartum depression may persist three years after giving birth

A study of 5,000 women has found that approximately 1 in 4 experienced high levels of depressive symptoms at some point in the three years after giving birth. The rest of the women experienced low levels of depression throughout the three-year span.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027083744.htm

Task Force Recommends Colon Cancer Screening at Age 45

The starting age was lowered due to an increase in colorectal cancer among younger people.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/task-force-colon-cancer-screening-age-45

Could Dietary Supplements Boost Breast Cancer Risk?

Some antioxidant supplements may offset the anticancer effects of chemotherapy.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/dietary-supplements-boost-breast-cancer-risk

Average body temperature among healthy adults declined over the past two decades

In the nearly two centuries since German physician Carl Wunderlich established 98.6°F as the standard 'normal' body temperature, it has been used by parents and doctors alike as the measure by which fevers -- and often the severity of illness -- have been assessed.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028171432.htm

Study helps explain why motivation to learn declines with age

Neuroscientists have identified a brain circuit critical for learning to make decisions that require evaluating the cost or reward of an action. They showed this circuit is negatively affected by aging and in Huntington's disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028171435.htm

A patch that could help heal broken hearts

According to the American Heart Association, heart disease is the leading cause of death worldwide in recent years. During a heart attack, or myocardial infarction (MI), a blocked artery and the resulting oxygen deprivation cause massive cardiac cell death, blood vessel impairment and inflammation. Now, researchers have developed a cardiac patch with tiny engineered blood vessels that improved recovery from MI in rats and pigs.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028124513.htm

New Report Adds Up the Financial Burden of a Cancer Diagnosis

The report found U.S. cancer patients in 2018 spent $5.6 billion in out-of-pocket costs for cancer treatment.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/finnacial-burden-cancer-diagnosis

Death rates among people with severe COVID-19 drop by a half in England

Death rates from people with severe COVID-19 in hospital have dropped to around a half of the rate at the peak of the pandemic, new research has revealed.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027105439.htm

Paracetamol poisonings up

In 2003, the painkiller paracetamol became available in Switzerland in tablets with a higher dose of the active ingredient. This correlates with an increase in cases of paracetamol poisoning in the country, as a data analysis shows.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028110635.htm

Genetic analysis system yields new insights into bacterial pneumonia

A team of infectious disease researchers has developed a new method to identify virulence genes in Streptococcus pneumoniae, the leading cause of bacterial pneumonia. Using this technique in a mouse model of pneumonia, they were able to gain new insights into the progression of the disease and its interaction with the flu virus.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028110631.htm

An artificial cell on a chip

Researchers have developed a precisely controllable system for mimicking biochemical reaction cascades in cells. Using microfluidic technology, they produce miniature polymeric reaction containers equipped with the desired properties. This 'cell on a chip' is useful not only for studying processes in cells, but also for the development of new synthetic pathways for chemical applications or for biological active substances in medicine.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028101840.htm

Specific and rapid expansion of blood vessels

Upon a heart infarct or stroke, rapid restoration of blood flow, and oxygen delivery to the hypo perfused regions is of eminent importance to prevent further damage to heart or brain. Arterial diameter is a critical determinant of blood flow conductance. Scientists have now discovered a novel mechanism to structurally increase arterial diameter by selectively increasing the size of arterial endothelial cells, thereby allowing rapid increases in flow.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028101838.htm

Estrogenic and anti-estrogenic effects of PFASs could depend on the presence of estrogen

Perfluoroalkyl substances (PFASs) have received intense scrutiny in recent years because of their persistence in the environment and potential endocrine-disrupting effects. However, their estrogenic activities are controversial, with different studies showing apparently contradictory results. Now, researchers have used a combination of laboratory experiments and computer modeling to reveal that PFASs can interact with the estrogen receptor in different ways to influence estrogen-controlled gene expression.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201028083000.htm

'Fast' MRI detects breast cancers that 3-D mammograms may miss

In a retrospective study of asymptomatic patients, all of whom had a negative 3-D mammogram within the previous 11 months, abbreviated MRI detected roughly 27 cancers per 1,000 women screened.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027111240.htm

New strategy for treating common retinal diseases shows promise

Scientists have uncovered a potential new strategy for treating eye diseases that affect millions of people around the world, often resulting in blindness.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027192408.htm

Scientists use clues in the human genome to discover new inflammatory syndrome

Researchers have discovered a new inflammatory disorder called vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic syndrome (VEXAS), which is caused by mutations in the UBA1 gene. VEXAS causes symptoms that included blood clots in veins, recurrent fevers, pulmonary abnormalities and vacuoles (unusual cavity-like structures) in myeloid cells.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027133725.htm

New tactic to stop the growth of a deadly brain cancer

Scientists have discovered a way to stop the growth of glioblastoma, the deadliest form of brain cancer. The finding provides a new tactic in the war against cancer that involves reprogramming the immune system to do what it does best - fight the tumor instead of fueling it.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027105359.htm

Langerhans cells are up to the job, they just need a chance

Researchers found that Langerhans cells (LCs) play a crucial role in mucocutaneous acute guest-versus-host disease (aGVHD). Their experiments in mice showed that when the LCs of a recipient were depleted, the formation of mucocutaneous lesions was enhanced because the infiltration of CD8+ T cells was inhibited. Their findings have significant implications for improving blood stem cell transplantation treatments and clinical outcomes for patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027105350.htm

Aerosol microdroplets inefficient carriers of COVID-19 virus

Aerosol microdroplets do not appear to be extremely efficient at spreading the virus that leads to COVID-19. While the lingering microdroplets are certainly not risk-free, due to their small size they contain less virus than the larger droplets that are produced when someone coughs, speaks, or sneezes directly on us, said researchers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027111234.htm

Random effects key to containing epidemics

Scientists have discovered why dividing a large population into multiple subpopulations that do not intermix can help contain outbreaks without imposing contact restrictions within those local communities.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027111233.htm

Black Hispanic individuals hardest hit by COVID-19

A new study shows the disproportionate impact of COVID-19 on Hispanic groups within the United States, with the most severe outcomes, including death and intensive care, among Hispanic Black individuals.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027111229.htm

Biomarkers could be used in a quick, inexpensive COVID-19 blood screening tool

A new study suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites -- small molecules broken down in the human body through the process of metabolism. Three specific metabolites identified in this study could act as biomarkers and one day be measured through an inexpensive blood test to quickly screen patients for the disease and predict which patients will become most critically ill.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027105414.htm

Scientists discover how a common mutation leads to 'night owl' sleep disorder

People with delayed sleep phase disorder are unable to fall asleep until late at night (often after 2 a.m.) and have difficulty getting up in the morning. In 2017, scientists discovered a surprisingly common mutation that causes this sleep disorder by altering a key component of the biological clock that maintains the body's daily rhythms. Now, a new study reveals the molecular mechanisms involved and point the way toward potential treatments.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027105354.htm

Over 80 percent of COVID-19 patients have vitamin D deficiency, study finds

Over 80 percent of 200 COVID-19 patients in a hospital in Spain have vitamin D deficiency, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027092216.htm

'White matter lesion' mapping tool identifies early signs of dementia

A new tool for analyzing tissue damage seen on MRI brain scans can detect with more than 70% accuracy early signs of cognitive decline, new research shows.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201027083748.htm

Risk score predicts prognosis of outpatients with COVID-19

A new artificial intelligence-based score considers multiple factors to predict the prognosis of individual patients with COVID-19 seen at urgent care clinics or emergency departments. The tool can be used to rapidly and automatically determine which patients are most likely to develop complications and need to be hospitalized.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026164416.htm

New COVID-19 related genes -- helpful and harmful -- found in massive screen

Researchers screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus. The pro-viral and anti-viral role of these genes will help guide scientists in development of new therapies to combat COVID-19, the researchers say.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026153944.htm

Ultrasounds show impact of COVID-19 on the heart

A new study identifies different types of cardiac structural damage experienced by COVID-19 patients after cardiac injury that can be associated with deadly conditions including heart attack, pulmonary embolism, heart failure, and myocarditis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026144522.htm

Tiny golden bullets could help tackle asbestos-related cancers

Gold nanotubes - tiny hollow cylinders one thousandth the width of a human hair - could be used to treat mesothelioma, a type of cancer caused by exposure to asbestos, according to a team of researchers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114220.htm

Study finds PTSD interacts with klotho gene, may cause premature aging in the brain

Genetics and the environment (including psychiatric stress) may contribute to the pace of cellular aging, causing some individuals to have a biological age that exceeds their chronological age.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114208.htm

Kid influencers are promoting junk food brands on YouTube -- garnering more than a billion views

Kids with wildly popular YouTube channels are frequently promoting unhealthy food and drinks in their videos, warn researchers.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026081501.htm

Latinos Working in Food Processing and Agriculture Face Greater COVID-19 Risk

About 70% of employees who contracted the coronavirus in these work settings were Hispanic.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/latinos-working-food-processing-agriculture-face-greater-covid19-risk

Artificially sweetened drinks may not be heart healthier than sugary drinks

Sugary drinks and artificially sweetened beverages are associated with a higher risk of cardiovascular disease, which suggests artificially sweetened beverages may not be the healthy alternative they are often claimed to be, according to a research letter.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026144524.htm

Healthcare as a climate solution

Although the link may not be obvious, healthcare and climate change -- two issues that pose major challenges around the world -- are in fact more connected than society may realize. So say researchers, who are increasingly proving this to be true.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026184029.htm

Localized vaccination surveillance could help prevent measles outbreaks

Access to more localized data on childhood vaccination coverage, such as at the school or neighborhood levels, could help better predict and prevent measles outbreaks in the United States, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026153946.htm

DrugCell: New experimental AI platform matches tumor to best drug combo

Researchers use experimental artificial intelligence system called DrugCell to predict the best approach to treating cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026164900.htm

New insights into a potential target for autoimmune disease

With insights into a molecular pathway that regulates the activity of Tregs, a type of T cell involved in immunosuppression, new research opens up possibly new avenues for treating inflammatory and autoimmune diseases.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026164426.htm

New map of the immune landscape in pancreatic cancer could guide immunotherapy

A new analysis highlights the diversity of immune response in pancreatic cancer, and points toward the need for treatments tailored to individual patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026164424.htm

Young Black Breast Cancer Survivors Star in Ads for Rihanna’s Lingerie

Savage X Fenty, the pop superstar’s brand, is known for its dedication to inclusive representation in popular culture.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/young-black-breast-cancer-survivors-star-ads-rihannas-lingerie

Most dentists have experienced aggression from patients

Roughly half of US dentists experienced verbal or reputational aggression by patients in the past year, and nearly one in four endured physical aggression, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026153942.htm

Microplastics in groundwater (and our drinking water) present unknown risk

Microplastics (plastics <5mm) and their negative health impacts have been studied in oceans, rivers, and even soils, and scientists are beginning to grapple with the myriad human health impacts their presence might have. One understudied, but critical, link in the cycle is groundwater, which is often a source of drinking water.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026153939.htm

Neuron-based gene expression study reveals insights on fear and its regulation

The expression of a gene called CREB in certain neurons may function as a switch to regulate feelings of fear and its extinction.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026135758.htm

Can scientists take the STING out of common respiratory viruses?

Scientists have made a curious discovery about a well-known human protein that helps the immune system fight viral infections. Researchers found that one class of viruses actually requires this protein to infect cells and replicate.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026135750.htm

Hard physical work may significantly increase the risk of dementia

Men in jobs with hard physical work have a higher risk of developing dementia compared to men doing sedentary work, new research reveals. The researchers therefore urge the health authorities to make their recommendations concerning physical activity more specific.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114240.htm

How exercise stalls cancer growth through the immune system

People with cancer who exercise generally have a better prognosis than inactive patients. Now, researchers have found a likely explanation of why exercise helps slow down cancer growth in mice: Physical activity changes the metabolism of the immune system's cytotoxic T cells and thereby improves their ability to attack cancer cells.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114229.htm

Single brain region links depression and anxiety, heart disease, and treatment sensitivity

Over-activity in a single brain region called the subgenual anterior cingulate cortex (sgACC) underlies several key symptoms of mood and anxiety disorders, but an antidepressant only successfully treats some of the symptoms. A new study suggests that sgACC is a crucial region in depression and anxiety, and targeted treatment based on a patient's symptoms could lead to better outcomes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026081457.htm

State gun laws may help curb violence across state lines: study

Researchers find that strong state firearm laws are associated with fewer firearm homicides -- both within the state where the laws are enacted and across state lines. Conversely, weak firearm laws in one state are linked to higher rates of homicides in neighboring states.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114242.htm

T-cells from recovered COVID-19 patients show promise to protect vulnerable patients from infection

T-cells taken from the blood of people who recovered from a COVID-19 infection can be successfully multiplied in the lab and maintain the ability to effectively target proteins that are key to the virus's function, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114218.htm

CRISPR screen identifies genes, drug targets to protect against SARS-CoV-2 infection

A new study demonstrates how changes in human genes can reduce SARS-CoV-2 infection and describes a wide array of genes that have not previously been considered as therapeutic targets for SARS-CoV-2.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114216.htm

Estimating risk of airborne COVID-19 with mask usage, social distancing

The Contagion Airborne Transmission inequality model illustrates correlation between physical distancing and protection, the efficacy of face masks and the impact of physical activity on transmission.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114206.htm

Tracking evolution of SARS-CoV-2 virus mutations

Researchers tracked the mutation rate in SARS-CoV-2 virus's proteome -- the collection of proteins encoded by genetic material -- through time, starting with the first SARS-CoV-2 genome published in January and ending more than 15,300 genomes later in May. The team found some regions still actively spinning off new mutations, indicating continuing adaptation to the host environment. But the mutation rate in other regions showed signs of slowing, coalescing around single versions of key proteins.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026114157.htm

New York City's coronavirus outbreak spread from more European sources than first reported

The COVID-19 pandemic started earlier than previously thought in New York City and Long Island by dozens of people infected mostly with strains from Europe. A new analysis also shows that most of the spread was within the community, as opposed to coming from people who had traveled.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026081449.htm

Coronavirus mutations show early safety measures and restrictions limited viral spread

Scientists analyzed genomic information from over 6,000 samples of SARS-CoV-2, the coronavirus behind the COVID-19 pandemic. Results show that early measures in states such as California and Washington were effective at limiting viral spread in the early phases of the pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022170235.htm

Researchers discover molecular link between diet and risk of colorectal cancer

Researchers have identified a direct molecular link between meat and dairy diets and the development of antibodies in the blood that increase the chances of developing cancer. This connection may explain the high incidence of cancer among those who consume large amounts of dairy products and red meat, similar to the link between high cholesterol and an increased risk of heart disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022151749.htm

Discoveries reshape understanding of gut microbiome

New findings could lead to new therapies for IBD and people who've had portions of their bowels removed due to conditions like colon cancer and ulcerative colitis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022144544.htm

Hydrogen sulfide helps maintain your drive to breathe

Researchers have found that the production of hydrogen sulfide gas is necessary to breathe normally. Inhibition of hydrogen sulfide production in rats prevented brain neurons that control breathing from functioning normally. These findings have identified new mediators of breathing that can now be explored in the context of human health and disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026095413.htm

Weight-reduction surgery for severely obese adults may prevent second heart attack, death

Adults with severe obesity (BMI >35) and a prior heart attack who undergo weight-reduction surgery may lower their risk of a second heart attack, major cardiovascular event, heart failure and death. The effect weight-reduction surgery had on the patients' weight, blood pressure, cholesterol and A1C (a Type 2 diabetes marker) seems to play a role in decreasing the risk of heart attack and death.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026081459.htm

Nearly one in three young adults in the US does not know common stroke symptoms

Nearly 30% of U.S. adults younger than 45 don't know all five of the most common stroke symptoms, according to a recent survey. Hispanic adults, people not born in the U.S. and less educated young adults were among the most likely to be unaware of stroke symptoms. Stroke incidence and hospitalizations are rising among young adults in the U.S.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201026081455.htm

Researchers reveal why heat stress damages sperm

Biologists have used the model organism Caenorhabditis elegans to identify molecular mechanisms that produce DNA damage in sperm and contribute to male infertility following exposure to heat.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023095855.htm

COVID-19 anxiety linked to body image issues

A new study has found that anxiety and stress directly linked to COVID-19 could be causing a number of body image issues. The research, which involved 506 UK adults, found that worries linked to COVID-19 were associated with body dissatisfaction and a desire for thinness in women, and associated with body fat dissatisfaction and a desire for muscularity in men.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022201407.htm

Scientist develops new way to test for COVID-19 antibodies

New research details how a cell-free test rapidly detects COVID-19 neutralizing antibodies and could aid in vaccine testing and drug discovery efforts.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022201404.htm

Malaria-preventive drugs dramatically reduce infections in school children

Use of preventive antimalarial treatments reduces by half the number of malaria infections among schoolchildren, according to a new analysis published today in The Lancet Global Health.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022183806.htm

Ancient origins of speed control during movement

Movement in animals is complex. Little has been known about how spinal inhibitory interneurons work to silence other neurons and related muscle groups in coordination with the active muscle groups across changing speeds. Now a research team has discovered in a study of zebrafish that there is a very orderly relationship between when these critical inhibitory neurons are born, their participation in different speeds of movement and what part of a motor neuron they innervate.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022144530.htm

New imaging method reveals HIV's sugary shield in unprecedented detail

Scientists have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules that help shield HIV from the immune system. Mapping these shields will give researchers a more complete understanding of why antibodies react to some spots on the virus but not others, and may shape the design of new vaccines that target the most vulnerable sites on viruses.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023191037.htm

New therapeutic approach against leukemia

Using an RNA molecule complex, researchers can prevent retention of cancer stem cell in their tumor supporting niche.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023123122.htm

Research team discovers molecular processes in kidney cells that attract and feed COVID-19

What about the kidneys make them a hotspot for COVID-19's cytokine storm? A research team says it's the presence of a protein found on specialized renal transport cells.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023123113.htm

PTSD and alcohol abuse go hand-in-hand, but males and females exhibit symptoms differently

Through intricate experiments designed to account for sex-specific differences, scientists have zeroed-in on certain changes in the brain that may be responsible for driving alcohol abuse among people with PTSD. In studies with rodents, researchers found that males and females exhibit their own distinct symptoms and brain features of PTSD and alcohol use disorder. Such differences are not typically accounted for in laboratory-based studies yet could lead to more successful clinical treatments.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023191035.htm

Hydroxychloroquine does not prevent COVID-19 in health care workers, trial shows

Researchers found that taking hydroxychloroquine once or twice weekly did not prevent the development of COVID-19 in health care workers better than the placebo.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021163929.htm

Financial Hardship Associated With Increased Mortality Risk

This association held true for people with or without a history of cancer.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/financial-hardship-associated-increased-mortality-risk

COVID-19 a double blow for chronic disease patients

The COVID-19 pandemic has escalated into a 'syndemic' for people with chronic illnesses, a new study analyzing data from low and middle-income countries shows.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023123141.htm

A new technique predicts how earthquakes would affect a city's hospitals

An international research team has developed a methodology to help disaster preparedness officials in large cities make contingency plans on a region-wide basis to make sure that emergency responders can get patients to the hospital facilities that are likeliest to remain in commission after a quake.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023095852.htm

34% of older adults in the US are prescribed potentially inappropriate drugs

The prescription of potentially inappropriate medications to older adults is linked to increased hospitalizations, and it costs patients, on average, more than $450 per year, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201023095850.htm

Aspirin use reduces risk of death in hospitalized COVID-19 patients

Hospitalized COVID-19 patients who were taking a daily low-dose aspirin to protect against cardiovascular disease had a significantly lower risk of complications and death compared to those who were not taking aspirin, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022195637.htm

Gut hormone blocks brain cell formation and is linked to Parkinson's dementia

A gut hormone, ghrelin, is a key regulator of new nerve cells in the adult brain, a research team has discovered. It could help pave the way for new drugs to treat dementia in patients with Parkinson's Disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022183809.htm

Details about broadly neutralizing antibodies provide insights for universal flu vaccine

New research from an immunology team may shed light on the challenges of developing a universal flu vaccine that would provide long-lasting and broad protection against influenza viruses.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022125510.htm

Technology shines the light on ovarian cancer treatments

A scientist and entrepreneur is working to use simple LED light to help determine if certain chemotherapy options will work for specific patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022083305.htm

Obesity and disease tied to dramatic dietary changes

The 'mismatch hypothesis' argues that our bodies evolved to digest the foods that our ancestors ate, and that human bodies will struggle and largely fail to metabolize a radically new set of foods. This intuitive idea is hard to test directly, but the Turkana, a pastoralist population in remote Kenya, present a natural experiment: genetically homogenous populations whose diets stretch across a lifestyle gradient from relatively 'matched' to extremely 'mismatched' with their recent evolutionary history.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021163945.htm

FDA Approves Remdesivir for Hospitalized COVID-19 Patients

The antiviral drug is the first treatment for the new coronavirus to be approved in United States.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/fda-approves-remdesivir-hospitalized-covid19-patients

OX40 Cancer Immunotherapy: What is it and Why is it Important?

OX40 immunotherapy is a new agent that shows tremendous promise in advanced cancer treatment. It is considered an immune co-stimulator or T cell co-stimulation. Essentially, it stimulates the immune system to fight tumors and cancer cells in the body.

When immunotherapy is combined with other cancer treatments, such as chemotherapy, patients are more likely to experience better outcomes. However, no two agents work the same for every patient, so it is essential to discuss with your oncologist if OX40 or another agent is the best option for your treatment. 

 

How Does OX40 Work?

Studies are now showing how agents such as OX40 can be injected directly into tumors. OX40 immunotherapy stimulates the immune system to fight against aggressive tumors. According to these studies, it is unnecessary to inject every tumor as the immune system responds to other cancer cells in the body once injected. It is, however, most important to inject the therapy at the primary tumor. Once these cells are “trained” to respond to fight the tumor, they can then respond to other cancer cells in the body.

 

What Do I Need to Know About CD40 cancer immunotherapy? 

CD40 is a member of the TNF (tumor necrosis factor) family. It is also an agent that activates the immune system to attack tumors. 

When combined with chemotherapy, CD40 cancer immunotherapy has shown promising results. It has demonstrated success in treating many types of cancer, including pancreatic cancer, melanomas, and mesothelioma. 

CD40 essentially helps activate cells that fight the tumor and make the tumor more responsive to chemotherapy agents. The agent activates cells called macrophages that enhance the delivery of chemotherapy to cancer cells. 

 

What are the limitations of OX40 Agonists and Other Immunotherapy Agents? 

There are limitations to OX40 and other cancer immunotherapy agents. Sometimes the body does not respond to fight the tumors. Some people respond better to specific agents compared to other people who receive the treatment. Research continues in this area as to what factors affect treatment response. 

There have been advancements in administering these therapies. Studies indicate injecting the agents directly into tumors through radiofrequency ablation fights cancer cells more effectively than intravenous injection alone. 

Furthermore, using cryoablation techniques, combined with the injection of agents such as ox40 and cd40 immunotherapy, seem to lead to better outcomes. Such outcomes appear to be somehow linked to the application of both treatment methods in tandem.

 

OX40 cancer immunotherapy – Why are Immunotherapy Agents Important? 

Agents such as OX40 and CD40 are very promising advanced cancer treatment options. In combination with other treatments, such as chemotherapy, they show success in treating tumors with decreased side effects. 

With an estimated 1.8 million Americans being diagnosed with cancer in 2020, the emergence of promising new treatment options, such as OX40 cancer immunotherapy, gives hope to patients and their families.

How Williams Cancer Institute Can Help 

Dr. Jason Williams combines his interventional radiology expertise with his knowledge of cancer, immunology, and immunotherapy. If you require advanced cancer treatment, Williams Cancer Institute can help. 

We have experience in radiofrequency ablation, Immuno-therapy agents, and chemotherapy options. Contact us for help in finding the right immunotherapy option for you. You can also schedule an appointment with our oncologist. 

 

 

 

References

National Cancer Institute (2020). Clinical trials using anti-OX40 monoclonal antibody. Retrieved from: https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/anti-ox40-monoclonal-antibody

 

The material contained on this site is for informational purposes only and DOES NOT CONSTITUTE THE PROVIDING OF MEDICAL ADVICE, and is not intended to be a substitute for independent professional medical judgment, advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions or concerns you may have regarding your health.

The post OX40 Cancer Immunotherapy: What is it and Why is it Important? appeared first on Williams Cancer Institute.

source https://williamscancerinstitute.com/ox40-cancer-immunotherapy-what-is-it-and-why-is-it-important/

A promising discovery could lead to better treatment for Hepatitis C

Virologists have identified a critical role played by a cellular protein in the progression of Hepatitis C virus infection, paving the way for more effective treatment. No vaccine currently exists for Hepatitis C virus infection, which affects more than 130 million people worldwide and nearly 250,000 Canadians. Antivirals exist but are expensive and not readily available in developing countries, where the disease is most prevalent.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022144532.htm

Toward a new staging system for prostate cancer, and why it matters

The development and validation of a staging system for non-metastatic prostate cancer could help doctors and patients assess treatment options, as well as improve clinical trials.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022123111.htm

Simplified method to modify disease signaling with light

Cellular optogenetics is a technique that allows researchers to use light to precisely control cell signaling and function in space and time enabling the investigation of mechanisms involved in disease processes. A research team has developed a novel way to make cellular optogenetic tools much easier to monitor and apply, and showed how they can be used to investigate the cellular side effects of medicines used to treat cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022112626.htm

Antiretroviral therapy can't completely stop accelerated cell aging seen in HIV

Untreated HIV infection is linked with epigenetic changes that suggest rapid aging. A new study shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns, leaving patients more susceptible to aging-related illnesses.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022112608.htm

Researchers solve 'protein paradox' and suggest way to exploit cancer weakness

Researchers have discovered how thus far a mysterious function of the so-called MCM proteins protect the human cells against DNA instability, which can cause devastating diseases including cancer. In addition to their known role as molecular motors of genome duplication, MCM proteins control the speed of this process. How cells manage to constrain the speed of DNA replication has puzzled researchers for decades and has even been called a 'MCM paradox'.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022112601.htm

Multiple sclerosis as the flip side of immune fitness

About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors. The decisive factor is the shaping of a repertoire of immune cells which - although they are effective in fighting off pathogens such as Epstein-Barr virus - also attack brain tissue.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022112554.htm

New approach to fighting cancer could reduce costs and side effects

Researchers have developed a novel approach based on microfluidic technology to 'purify' the immune cells of patients in the fight against cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022093956.htm

Finally, a way to see molecules 'wobble'

Researchers have found a way to visualize those molecules in even greater detail, showing their position and orientation in 3D, and even how they wobble and oscillate. This could shed invaluable insights into the biological processes involved, for example, when a cell and the proteins that regulate its functions react to a COVID-19 virus.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022112618.htm

Preventing lead poisoning at the source

Using a variety of public records, researchers examined every rental property in Cleveland from 2016-18 on factors related to the likelihood that the property could have lead-safety problems.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022093944.htm

Drinking green tea and coffee daily linked to lower death risk in people with diabetes

Drinking plenty of both green tea and coffee is linked to a lower risk of dying from any cause among people with type 2 diabetes, suggests new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020190129.htm

Turbulent era sparked leap in human behavior, adaptability 320,000 years ago

The first analysis of a sedimentary drill core representing 1 million years of environmental history in the East African Rift Valley shows that at the same time early humans were abandoning old tools in favor of more sophisticated technology and broadening their trade, their landscape was experiencing frequent fluctuations in vegetation and water supply that made resources less reliably available. The findings suggest that instability in their landscape was a key driver of human adaptability.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021140919.htm

Steroid inhalers/pills for asthma linked to heightened risk of brittle bones and fractures

Taking steroid inhalers or tablets to treat asthma or control flare-ups is linked to a heightened risk of brittle bones (osteoporosis) and increased vulnerability to broken bones (fragility fractures), finds new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020190126.htm

SARS-CoV-2 May Use Key Carbohydrate to Infect Cells

A carbohydrate called heparan sulfate, found on cell surfaces, may help the new coronavirus infects cells.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/sarscov2-may-use-key-carbohydrate-infect-cells

Bacterial metabolism of dietary soy may lower risk factor for dementia

A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia - with the help of the right bacteria, according to a new discovery.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201022083311.htm

Innovation spins spider web architecture into 3D imaging technology

Innovators are taking cues from nature to develop 3D photodetectors for biomedical imaging. The researchers used some architectural features from spider webs to develop the technology.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021085058.htm

Highly effective tumor detection strategy for common childhood brain tumors

A team of scientists have developed a way to more accurately both detect and monitor a common type of pediatric brain cancer, setting the stage for giving clinicians a real-time view into how the cancer responds to treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021163932.htm

DNA: At our cores, we're all strengthened by 'dumbbells'

Scientists detail the structure of dumbbell-like sequences in DNA during interphase that suggest several unseen aspects of chromosome configuration and function.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021140912.htm

Tumor DNA in spinal fluid could help doctors better monitor childhood brain cancer

Researchers have demonstrated that a new liquid biopsy approach overcomes traditional barriers to quickly and efficiently diagnose and monitor high-grade pediatric gliomas.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021130148.htm

New theory sheds light on how the environment influences human health

Researchers have proposed a groundbreaking new way to study the interaction between complex biological systems in the body and the environment. Their theory suggests the existence of 'biodynamic interfaces,' an intermediate entity between the two realms, as opposed to conventional approaches that analyze individual aspects of the interaction between the environment and humans in isolation, according to a new article.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020131349.htm

The biological 'record' of extremely preterm birth differs in men and women

Researchers have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely preterm.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020131342.htm

Genome archeologists discover path to activate immune response against cancer

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021140910.htm

Delivering proteins to testes could someday treat male infertility

According to the Mayo Clinic, about 15% of couples are infertile, and male infertility plays a role in over one-third of these cases. Often, problems with sperm development are to blame. Now, researchers have found a way to deliver a protein important for sperm cell production directly to mouse testicles, where it restored normal sperm development and allowed previously infertile mice to father pups.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021130145.htm

Chili-shaped device could reveal just how hot that pepper is

Some people love spicy food -- the hotter, the better. Others go out of their way to avoid the palate-singeing burn of capsaicin, the compound that gives chili peppers their kick. Now, researchers have developed a portable device (whimsically shaped like a chili pepper) that can reveal how much capsaicin a pepper contains, before biting into it.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021130139.htm

Women With Inflammatory Breast Cancer Are Living Longer

But persistent racial disparities mean Black women diagnosed with the aggressive disease have a shorter life expectancy.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/women-inflammatory-breast-cancer-living-longer

Observed COVID-19 variability may have underlying molecular sources

People have different susceptibilities to SARS-CoV-2, the virus behind the COVID-19 pandemic, and develop varying degrees of fever, fatigue, and breathing problems -- common symptoms of the illness. What might explain this variation? Scientists may have an answer to this mystery.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021140915.htm

Americans' responses to COVID-19 stay-home orders differed according to population density

Americans strongly reduced their visits to grocery stores, pharmacies, and transit stations following stay-at-home orders from mayors and governors earlier this year, but did not reduce their visits to parks and beaches.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021130136.htm

Transcription factors may inadvertently lock in DNA mistakes

A team of researchers has found that transcription factors have a tendency to bind strongly to 'mismatched' sections of DNA, i.e. sections of the genome that were not copied correctly. The strong binding of transcription factors to these mismatched sections of regulatory DNA might be a way in which random mutations become a problem that leads to disease, including cancer.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021112356.htm

Scientists take major step toward Angelman Syndrome gene therapy

Babies born with a faulty maternal copy of the UBE3A gene will develop Angelman syndrome, a severe neurodevelopmental disorder with no cure and limited treatments. Now, for the first time, scientists show that gene editing and gene therapy techniques can be used to restore UBE3A in human neuron cultures and treat deficits in an animal model of Angelman syndrome.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021112346.htm

Diagnosing Parkinson's disease with skin samples could lead to earlier detection

New research shows a simple skin test can accurately identify Parkinson's disease, which could lead to earlier detection of the disease and better outcomes for patients. Currently, Parkinson's disease is diagnosed by clinical signs and symptoms but only definitively diagnosed at autopsy. The researchers conducted a blinded study of 50 skin samples using an assay originally designed to detect mad cow disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021112343.htm

Vitamin A boosts fat burning in cold conditions

A recent study shows that cold ambient temperatures increase vitamin A levels in humans and mice. This helps convert 'bad' white adipose tissue into 'good' brown adipose tissue which stimulates fat burning and heat generation.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021112318.htm

Virtual Reality health appointments can help patients address eating disorders

Research has revealed that Virtual Reality (VR) technology can have significant impact on the validity of remote health appointments for those with eating disorders, through a process called Virtual Reality Exposure Therapy (VRET).

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021111605.htm

Congress must clarify limits of gene-editing technologies

How the next Congress decides to handle the issue editing human sperm and eggs will affect the science, ethics and financing of genomic editing for decades to come, said a law professor who studies the ethical and policy implications of advanced biotechnologies.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021111558.htm

Evidence review confirms CDC guidance about infectivity of novel coronavirus

A new review of dozens of studies suggests that people may shed virus for prolonged periods, but those with mild or no symptoms may be infectious for no more than about 10 days. People who are severely ill from COVID-19 may be infectious for as long as 20 days, according to the review.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021085113.htm

High flavanol diet may lead to lower blood pressure

People who consume a diet including flavanol-rich foods and drinks, including tea, apples and berries, could lead to lower blood pressure, according to the first study using objective measures of thousands of UK residents' diet.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021085109.htm

Hypothyroidism in pregnant mothers linked to ADHD in their children

Low levels of key, body-regulating chemicals in mothers during the first three months of pregnancy may interfere with the baby's brain development, a large study shows.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021085107.htm

Community noise may affect dementia risk

Results from a new study support emerging evidence suggesting that noise may influence individuals' risk of developing dementia later in life.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021085106.htm

Phase 3 clinical trial to treat mild Alzheimer's disease using deep brain stimulation

Medical researchers are enrolling individuals in an international phase 3 clinical trial to examine the safety and effectiveness of deep brain stimulation to treat Alzheimer's. The study uses electrical impulses to stimulate the region of the brain known as the fornix, which is associated with memory and learning.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201021085100.htm

High levels of microplastics released from infant feeding bottles during formula prep

New research shows that high levels of microplastics (MPs) are released from infant-feeding bottles (IFBs) during formula preparation. The research also indicates a strong relationship between heat and MP release, such that warmer liquids (formula or water used to sterilize bottles) result in far greater release of MPs. The work underlines the need for appropriate mitigation strategies and new plastic technologies.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020190131.htm

Light pollution may increase biting behavior at night in Aedes aegypti mosquitoes

Artificial light abnormally increases mosquito biting behavior at night in a species that typically prefers to bite people during the day, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020161202.htm

Repairing the photosynthetic enzyme Rubisco

Researchers have elucidated how Rubisco activase works. As the name indicates, this enzyme is critical for repairing Rubisco once it has lost its activity.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020150512.htm

Salt-based mosquito-control products are ineffective

A new study by a bevy of expert mosquito researchers offers an important warning to consumers: Products claiming to reduce mosquito populations with salt-water solutions are ineffective. In a series of lab tests using nine mosquito species, researchers found no evidence that adult mosquitoes are killed by salt ingested at concentrations used in several popular mosquito-control products.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020105543.htm

New anti-AB vaccine could help halt Alzheimer's progression, preclinical study finds

A preclinical study by neuroscientists indicates that an antigen-presenting dendritic vaccine with a specific antibody response to oligomeric A-beta may be safer and offer clinical benefit in treating Alzheimer's disease. The vaccine uses immune cells known as dendritic cells loaded with a modified A beta peptide as the antigen.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020135637.htm

Cutting-edge, whole-heart imaging provides new details on heart defects

A cutting-edge technique that allows scientists to zoom into tiny details in a 3D image of a whole animal heart may lead to new insights on congenital heart disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020131359.htm

Targeting the shell of the Ebola virus

As the world grapples with COVID-19, the Ebola virus is again raging. Researchers are using supercomputers to simulate the inner workings of Ebola (as well as COVID-19), looking at how molecules move, atom by atom, to carry out their functions. Now, they have revealed structural features of the Ebola virus's protein shell to provide therapeutic targets to destabilize the virus and knock it out with an antiviral treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020131355.htm

Cognitive behavioral therapy reduces insomnia symptoms among young drinkers

More than half of young adults at risk for alcohol-related harm report symptoms of insomnia. Cognitive behavioral therapy (CBT) is one of the first-line treatments for insomnia, but it's never been tested on young adults who are actively drinking. Researchers evaluated CBT's effect on young adult binge drinkers with insomnia to determine if this treatment can improve their sleep and potentially affect alcohol use outcomes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020131347.htm

Does the new heart transplant allocation policy encourage gaming by providers?

A new national policy was created to make determining who receives a heart transplant more fair. But new data shows it changed some practice patterns, too.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020131345.htm

Coronavirus vaccines stir doubts among many people worldwide, new study shows

A new study highlights potential global hesitancy to accept a COVID-19 vaccine. Based on data collected with the previously validated COVID-SCORE survey of a sample of over 13,400 individuals from 19 countries that have been hard-hit by the virus, the investigators found that 72 percent of participants would likely take the vaccine. Of the remaining 28 percent, 14 percent would refuse, while 14 percent would hesitate, which translates into tens of millions of potential vaccine avoiders.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020131340.htm

Actor Jeff Bridges Reveals His Lymphoma Diagnosis

He didn’t provide many details but said he would be undergoing treatment.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/actor-jeff-bridges-reveals-lymphoma-diagnosis

CRISPR meets Pac-Man: New DNA cut-and-paste tool enables bigger gene edits

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020105551.htm

New tool pulls elusive COVID-19 marker from human blood

Researchers have created a surface that repels every other element of human blood except an elusive cytokine critical to understanding the progress of COVID-19 in individual patients.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020105536.htm

Coronavirus: Study finds further door opener into the cell

The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. Researchers have now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells' interior. Neuropilin-1 is localized in the respiratory and olfactory epithelia.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020105526.htm

Neuropilin-1 drives SARS-CoV-2 infectivity, finds breakthrough study

Researchers have potentially identified what makes SARS-CoV-2 highly infectious and able to spread rapidly in human cells. The findings describe how the virus's ability to infect human cells can be reduced by inhibitors that block a newly discovered interaction between virus and host, demonstrating a potential anti-viral treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020105522.htm

COVID-19: Distancing and masks -- good but not enough

Decades-old data is being used to describe the propagation of tiny droplets. Now a fluid dynamics team has developed new models: Masks and distancing are good, but not enough. Even with a mask, infectious droplets can be transmitted over several meters and remain in the air longer than previously thought.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020111329.htm

Focal epilepsy often overlooked

Having subtler symptoms, a form of epilepsy that affects only one part of the brain often goes undiagnosed long enough to cause unexpected seizures that contribute to car crashes, a new study finds.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020081743.htm

Study shows active older adults have better physical and mental health

Older adults with higher physical activity and lower sitting time have better overall physical and mental health, according to a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020081740.htm

Cannabis reduces OCD symptoms by half in the short-term

People with obsessive-compulsive disorder (OCD) report that the severity of symptoms was reduced by about half within four hours of smoking cannabis. After smoking cannabis, users with OCD reported it reduced their compulsions by 60%, intrusions, or unwanted thoughts, by 49% and anxiety by 52%. The study also found that higher doses and cannabis with higher concentrations of CBD were associated with larger reductions in compulsions.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201020081733.htm

Updated: Rush Limbaugh Talks About Treatment for His Advanced Lung Cancer and His "Death Sentence"

The conservative radio talk show titan told listeners that he hopes to continue to stay on the air as much as he can.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/rush-limbaugh-advanced-lung-cancer

Patients who had more severe COVID-19 may be the best donors for convalescent plasma therapy

Sex, age, and severity of disease may be useful in identifying COVID-19 survivors who are likely to have high levels of antibodies that can protect against the disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019164942.htm

Criteria to predict cytokine storm in COVID-19 patients identified

Researchers have developed and validated predictive criteria for early identification of COVID-19 patients who are developing hyperimmune responses, raising the possibility for early therapeutic intervention.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019125534.htm

New lab test clarifies the potential protective effects of COVID-19 antibodies

Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn't tell you everything about your immunity. Scientists have developed a new lab testing procedure for the detection of antibodies against SARS-CoV-2 that gives results more quickly than existing assays and specifically identifies so-called 'neutralizing' antibodies.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019125514.htm

Mouthwashes, oral rinses may inactivate human coronaviruses, study finds

Certain oral antiseptics and mouthwashes may have the ability to inactivate human coronaviruses, according to a new study. The results indicate that some of these products might be useful for reducing the viral load, or amount of virus, in the mouth after infection and may help to reduce the spread of SARS-CoV-2, the coronavirus that causes COVID-19.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019125503.htm

Scientists find medieval plague outbreaks picked up speed over 300 years

Researchers who analyzed thousands of documents covering a 300-year span of plague outbreaks in London, England, have estimated that the disease spread four times faster in the 17th century than it had in the 14th century.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019155926.htm

Restoration of retinal and visual function following gene therapy

A breakthrough study results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019155922.htm

Immune activation in the liver illuminated with new glycan-tagging strategy

A signaling system implicated in liver fibrosis and immune activation is better understood thanks to this creative chemical fishing lure.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019133658.htm

Scientists map the human proteome

Twenty years after the release of the human genome, the genetic 'blueprint' of human life, an international research team has now mapped the first draft sequence of the human proteome.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019133648.htm

For toddlers with autism, more intervention hours are not necessarily better

Two prominent early intervention models for toddlers with autism show a very similar impact, whether delivered at 15-hours or 25-hours per week intensities, a study has found.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019133644.htm

COVID-19 More Severe for Some Minorities at Different Stages of the Disease

Black patients are more likely to require hospitalization, while Asian patients are at greater risk of dying in the hospital.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/covid19-severe-minorities-different-stages-disease

An ultrasonic projector for medicine

A chip-based technology that modulates intensive sound pressure profiles with high resolution opens up new possibilities for ultrasound therapy.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019125522.htm

Lullabies in any language relax babies

Researchers have determined that American infants relaxed when played lullabies that were unfamiliar and in a foreign language. The new findings supported the latter hypothesis: infants responded to universal elements of songs, despite the unfamiliarity of their melodies and words, and relaxed. The researchers also predict that the results could be replicated with a different group of subjects from another culture.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019112115.htm

AI methods of analyzing social networks find new cell types in tissue

In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated. Researchers have now developed an entirely new method of image analysis. Based on algorithms used in artificial intelligence, the method was originally devised to enhance understanding of social networks.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019111918.htm

Hand-held device reads levels of cancer biomarker

Researchers have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019103512.htm

Exercise and nutrition regimen benefits physical, cognitive health

Researchers studied the effects of a 12-week exercise regimen on 148 active-duty Air Force airmen, half of whom also received a twice-daily nutrient beverage that included protein; the omega-3 fatty acid, DHA; lutein; phospholipids; vitamin D; B vitamins and other micronutrients; along with a muscle-promoting compound known as HMB. Both groups improved in physical and cognitive function, with added gains among those who regularly consumed the nutritional beverage, the team reports.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019103508.htm

The 'goldilocks day': The perfect day for kids' bone health

Not too little, not too much - Goldilocks' 'just right' approach can now assess children's daily activities as new research confirms the best make up of a child's day to maximize bone health and function in children.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019103501.htm

Research could lead to customized cochlear implants

Researcher have analyzed the accuracy of predictions for cochlear implant outcomes, with a view to further improve their performance in noisy environments.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019103457.htm

Natural killer cells also have a memory function

Good news for the human immune system: researchers have managed to ascribe an immunological memory function to a subset of cytotoxic NK cells, which have hitherto been regarded as antigen-non-specific.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019103453.htm

Changes in blood metabolite profile are visible years before diagnosis of alcohol-related disease

A new study has shown that the serum metabolite profile can be used to identify individuals likely at risk of developing an alcohol-related disease in the future. The finding also opens up new avenues for preventing alcohol-related adverse effects.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019103439.htm

How cancer cells escape crowded tumors

When trapped in a crowded environment, cells of the human body try to escape. Scientists now discovered that it is the cell nucleus, which triggers the 'evasion reflex'. This reflex is activated once cell compression exceeds the size of the nucleus. This unexpected finding could help to predict treatment response and metastatic spreading of tumors.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019090121.htm

One-two punch of symptoms that exacerbate Alzheimer's

A new Alzheimer's study found that impaired blood flow in the brain is correlated with the buildup of tau tangles, a hallmark indicator of cognitive decline.The work suggests that treatments targeting vascular health in the brain -- as well as amyloid plaques and tau tangles -- may be more effective in preserving memory.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016090155.htm

Big babies could be at higher risk of common heart rhythm disorder in adulthood

Elevated birth weight is linked with developing atrial fibrillation later in life, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201019082907.htm

Remdesivir for COVID-19 Shows No Survival Benefit in Large Study

None of the four drugs tested in the WHO study reduced mortality or duration of hospitalization.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/remdesivir-covid19-shows-survival-benefit-large-study

Fats fighting back against bacteria

With antibiotic-resistant superbugs on the rise, this research shows a new way that cells are using to protect themselves - using fats as a covert weapon, and giving us new insights into alternative ways to fight infection.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016143050.htm

Calcium bursts kill drug-resistant tumor cells

Multidrug resistance (MDR) -- a process in which tumors become resistant to multiple medicines -- is the main cause of failure of cancer chemotherapy. Tumor cells often acquire MDR by boosting their production of proteins that pump drugs out of the cell, rendering the chemotherapies ineffective. Now, researchers have developed nanoparticles that release bursts of calcium inside tumor cells, inhibiting drug pumps and reversing MDR.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016132017.htm

Investigational ALS drug prolongs patient survival in clinical trial

An experimental medication that was recently shown to slow the progression of amyotrophic lateral sclerosis has now demonstrated the potential to also prolong patient survival. The findings come from a recent clinical trial.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016112859.htm

Octopus-inspired sucker transfers thin, delicate tissue grafts and biosensors

Thin tissue grafts and flexible electronics have a host of applications for wound healing, regenerative medicine and biosensing. A new device inspired by an octopus's sucker rapidly transfers delicate tissue or electronic sheets to the patient, overcoming a key barrier to clinical application.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016164312.htm

New research comparing HIV medications set to change international recommendations

A new study is set to change international treatment recommendations for people who are newly diagnosed with HIV -- an update that could affect nearly two million people per year worldwide.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016164308.htm

Personality traits affect shelter at home compliance

A worldwide survey conducted during the first wave of the COVID-19 pandemic found that people with certain common personality traits were less likely to shelter at home when government policies were less restrictive.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015090439.htm

Is Oral Cancer Pain a Sign That the Disease Has Spread?

Those who experience high levels of pain are more likely to have their cancer metastasize to the neck’s lymph nodes.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/oral-cancer-pain-sign-disease-spread

Viral 'molecular scissor' is next COVID-19 drug target

Inhibiting the SARS-CoV-2-PLpro enzyme is a novel avenue to explore in rational design of COVID-19 drugs, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016164310.htm

Existing medications may fight coronavirus infection

Researchers have identified three existing drugs with the potential to clear SARS-CoV-2 infections.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016143047.htm

Fraction of money earmarked for COVID-19 recovery could boost climate efforts

Global stimulus plans for economic recovery after the pandemic could easily cover climate-friendly policies, suggests a new study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015173135.htm

Boost to develop microalgae into health foods

A new discovery may provide the crucial link that helps accelerate development of microalgae into beneficial human health supplements.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015101830.htm

Risk of heart complications after major surgery is higher than previously thought

One in five high-risk patients undergoing major non-cardiac surgery will develop one or more heart complications within a year, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201014201017.htm

Young adults face higher risk of severe disease from infections than school-age children

The first systematic review of how the severity of infectious diseases changes with age suggests that the human immune system might start to lose the ability to protect against infections earlier than previously thought, according to new research.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201014201013.htm

Study explains the process that exacerbates MS

People with multiple sclerosis (MS) gradually develop increasing functional impairment. Researchers have now found a possible explanation for the progressive course of the disease in mice and how it can be reversed. The study can prove valuable to future treatments.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016143052.htm

Pinpointing the 'silent' mutations that gave the coronavirus an evolutionary edge

Researchers have identified a number of 'silent' mutations in the roughly 30,000 letters of the COVID-19 virus's genetic code that helped it thrive once it made the leap from bats and other wildlife to humans -- and possibly helped set the stage for the global pandemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016122403.htm

Is sitting always bad for your mind? A new study suggests maybe not

It's generally accepted health advice that adults of all ages should sit less, move more, and engage in regular exercise to feel better and reduce the risk of chronic diseases. However, when it comes to the brain and cognition, a new study of older adults suggests that some sedentariness isn't all bad, so long as basic physical activity benchmarks are being met.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016114924.htm

Could excessive sugar intake contribute to aggressive behaviors, ADHD, bipolar disorder?

New research suggests that conditions such as attention deficit hyperactivity syndrome (ADHD), bipolar disorder, and even aggressive behaviors may be linked with sugar intake, and that it may have an evolutionary basis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016112903.htm

Plant genetic engineering to fight 'hidden hunger'

More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins. Poor people in developing countries are most affected, as their diets are typically dominated by starchy staple foods, which are inexpensive sources of calories but contain low amounts of micronutrients. Researchers now explain how plant genetic engineering can help to sustainably address micronutrient malnutrition.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016090222.htm

Researchers make counterintuitive discoveries about immune-like characteristics of cells

Biologists reveal that tissue perturbations by chemotherapy agents promote stem cell expansion and that fibroblast cells exhibit unexpected, immune-like behavior.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016090220.htm

Gel instrumental in 3D bioprinting biological tissues

The eventual creation of replacement biological parts requires fully three-dimensional capabilities that two-dimensional and three-dimensional thin-film bioprinting cannot supply. Now, using a yield stress gel, engineers can place tiny aggregates of cells exactly where they want to build the complex shapes that will be necessary to replace bone, cartilage and other tissues.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201016090213.htm

Shannen Doherty’s Breast Cancer Update: “I’ve Got A Lot of Life in Me”

The actress says she’s got much more to do.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/shannen-dohertys-breast-cancer-update-got-lot-life

Not All Prostate Cancers Are Equally Aggressive

Researchers found that aggressive Gleason grade group 5 prostate cancer has different subtypes with varying risks.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/prostate-cancers-equally-aggressive

Long-Term Breast Cancer Survivors May Also Have Long-Term Side Effects

Radiation and chemotherapy treatment were associated with higher rates of mental and physical issues lasting up to a decade.


from Cancer Health RSS - Categories https://www.cancerhealth.com/article/longterm-breast-cancer-survivors-may-also-longterm-side-effects

Most effective drugs for common type of neuropathic pain

More than 20 million people in the U.S. suffer neuropathic pain. At least 25% of those cases are classified as unexplained and considered cryptogenic sensory polyneuropathy (CSPN). There is no information to guide a physician's drug choices to treat CSPN, but a researcher recently led a first-of-its-kind prospective comparative effectiveness study.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015173129.htm

Ingestible capsule that could help demystify the gut-brain axis

A team of experts from engineering, neuroscience, applied microbiology, and physics has been making headway on building a platform that can monitor and model the real-time processing of gut microbiome serotonin activity.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015173128.htm

Treating ringing in the ears with Sound and electrical stimulation of the tongue

In the largest clinical trial of its kind, researchers show that combining sound and electrical stimulation of the tongue can significantly reduce tinnitus, commonly described as 'ringing in the ears.' They also found that therapeutic effects can be sustained for up to 12 months post-treatment.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015173126.htm

Bark beetle outbreaks benefit wild bee populations, habitat

Researchers found significant increases in floral abundance and wild bee diversity in outbreak-affected forests, compared to similar, undisturbed forest.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015173124.htm

Framework for gauging health impacts of self-driving vehicles

Autonomous vehicles (AV) are the wave of the future in the automobile industry, and there's extensive discussion about the impacts on transportation, society, the economy and the environment. However, less attention has been focused on the potential health impacts of self-driving vehicles.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015173122.htm

Trigger that leads to faster nerve healing

Damaged nerves regenerate faster when protein clusters are broken apart, releasing mRNAs that can be used to rebuild the nerve. Scientists have found the trigger that could be used to accelerate regrowth more.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015134212.htm

A new approach boosts lithium-ion battery efficiency and puts out fires, too

Building new functionality into an overlooked lithium-ion battery component addresses two major goals of battery research: extending the driving range of electric vehicles and reducing the danger that laptops, cell phones and other devices will burst into flames.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015111738.htm

Inexpensive and rapid testing of drugs for resistant infections possible

A rapid and simple method for testing the efficacy of antibacterial drugs on infectious microbes has been developed and validated.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015111733.htm

Machine learning uncovers potential new TB drugs

Using a machine-learning approach that incorporates uncertainty, researchers identified several promising compounds that target a protein required for the survival of the bacteria that cause tuberculosis.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015111731.htm

Ultrasound technique offers more precise, quantified assessments of lung health

Researchers have developed a technique that uses ultrasound to provide non-invasive assessments of pulmonary fibrosis and pulmonary edema. The technique has been shown to both quantify lung scarring and detect lung fluid in rats. A study on pulmonary edema in humans is under way.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015111725.htm

Athletes fear being judged as weak when they experience pain or injury

Researchers have carried out the first multi-centered, international, qualitative study exploring the athlete experience (in their own words) of sporting low back pain (LBP). The study found a culture of concealment of pain and injury in rowers, leading to poor outcomes for these athletes.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015101838.htm

Repurposing drugs for a pan-coronavirus treatment

A new study identifies drug targets common to all three coronaviruses (SARS-CoV-2, SARS-CoV-1, and MERS-CoV) and potential drugs that could be repurposed as COVID-19 treatments. Researchers suggest that repurposed pan-coronavirus therapeutics may offer a rapid treatment response against future emerging coronavirus strains.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015101822.htm

Will the COVID-19 virus become endemic?

A new article explores the potential for the COVID-19 virus to become endemic, a regular feature producing recurring outbreaks in humans.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015101820.htm

Novel antiviral strategy for treatment of COVID-19

Researchers have discovered a novel antiviral strategy for treatment of COVID-19 using existing metallodrugs.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015101807.htm

A new toolkit for capturing how COVID-19 impacts crime

A new set of assessment tools shows promise in capturing how the COVID-19 pandemic affects patterns of criminal activity.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201014141142.htm

Predicting influenza epidemics

Researchers have developed a unique method to predict influenza epidemics by combining several sources of data. The forecasts can be used, for example, when planning healthcare provision, such that resources can be redistributed in the best possible manner and give everyone the best possible care during an epidemic.

from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/10/201015101805.htm