Researchers showed that na enzyme functions in genome maintenance by preventing double-stranded breaks in DNA during brain development in mice. In mice lacking this enzyme, these breaks occurred during epigenetic regulation of gene expression in the developing hippocampus, peaking two weeks after birth. The increased breaks were associated with abnormal neuronal dendrites and poor memory ability.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/11/201111122806.htm
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