A comparison of normal and germ-free mice revealed that as much as 70% of a mouse's gut chemistry is determined by its gut microbiome. Even in distant organs, such as the uterus or the brain, approximately 20% of molecules were different in the mice with gut microbes.
from Health & Medicine News -- ScienceDaily https://www.sciencedaily.com/releases/2020/02/200226131312.htm
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